TY - JOUR
T1 - Treatment with gonadotropin-releasing hormone (GnRH) antagonists in women suppressed with GnRH agonist may avoid cycle cancellation in patients at risk for ovarian hyperstimulation syndrome
AU - Gustofson, Robert L.
AU - Larsen, Frederick W.
AU - Bush, Mark R.
AU - Segars, James H.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2006/1
Y1 - 2006/1
N2 - Forty-seven patients at high risk for ovarian hyperstimulation syndrome because of markedly elevated serum E2 levels on either long-luteal or microdose flare leuprolide acetate regimens were treated with ganirelix acetate. Despite being pretreated with GnRH agonist and without withholding gonadotropins, serum E2 decreased by 49.5% and 41.0% of pretreatment values (long luteal and microdose flare, respectively) after initiation of ganirelix, and 68.1% of the patients became pregnant.
AB - Forty-seven patients at high risk for ovarian hyperstimulation syndrome because of markedly elevated serum E2 levels on either long-luteal or microdose flare leuprolide acetate regimens were treated with ganirelix acetate. Despite being pretreated with GnRH agonist and without withholding gonadotropins, serum E2 decreased by 49.5% and 41.0% of pretreatment values (long luteal and microdose flare, respectively) after initiation of ganirelix, and 68.1% of the patients became pregnant.
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U2 - 10.1016/j.fertnstert.2005.07.1291
DO - 10.1016/j.fertnstert.2005.07.1291
M3 - Article
C2 - 16412770
AN - SCOPUS:30344433463
SN - 0015-0282
VL - 85
SP - 251
EP - 254
JO - Fertility and sterility
JF - Fertility and sterility
IS - 1
ER -