Treatment of tourette syndrome

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The Gilles de la Tourette syndrome (TS) is a chronic, inherited neuropsychiatric disorder characterized by the presence of involuntary motor and phonic tics that wax and wane. Although once considered a rare disorder, the prevalence of TS may be as high as 3.5% of school-aged children. In addition to tics, individuals with TS often have a variety of concomitant psychopathologies including obsessive compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), learning difficulties, and sleep abnormalities. Although the presence of neurobehavioral problems is not required for the diagnosis of TS, their clinical impact on the patient may be more significant than the tics themselves. Tourette syndrome is an inherited disorder (specific gene and mode of inheritance remain unclear), but nongenetic environmental factors can influence tic frequency and severity. Pathophysiologically, tics arise within cortico-striatal-thalamo-cortical pathways and likely represent a dysfunction of synaptic neurotransmission.

Original languageEnglish (US)
Title of host publicationTreatment of Pediatric Neurologic Disorders
PublisherCRC Press
Pages125-132
Number of pages8
ISBN (Electronic)9780849340888
ISBN (Print)0824726936, 9780824726935
StatePublished - Jan 1 2005

Fingerprint

Tics
Tourette Syndrome
Therapeutics
Corpus Striatum
Waxes
Obsessive-Compulsive Disorder
Attention Deficit Disorder with Hyperactivity
Psychopathology
Synaptic Transmission
Sleep
Learning
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Singer, H. (2005). Treatment of tourette syndrome. In Treatment of Pediatric Neurologic Disorders (pp. 125-132). CRC Press.

Treatment of tourette syndrome. / Singer, Harvey.

Treatment of Pediatric Neurologic Disorders. CRC Press, 2005. p. 125-132.

Research output: Chapter in Book/Report/Conference proceedingChapter

Singer, H 2005, Treatment of tourette syndrome. in Treatment of Pediatric Neurologic Disorders. CRC Press, pp. 125-132.
Singer H. Treatment of tourette syndrome. In Treatment of Pediatric Neurologic Disorders. CRC Press. 2005. p. 125-132
Singer, Harvey. / Treatment of tourette syndrome. Treatment of Pediatric Neurologic Disorders. CRC Press, 2005. pp. 125-132
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