Treatment of Sympathomimetic Induced Intraventricular Hemorrhage with Intraventricular Urokinase

Wendy C. Ziai; Antigone Triantaphyllopoulou; Alexander Y. Razumovsky; Daniel F. Hanley

doi:10.1016/j.jstrokecerebrovasdis.2003.09.011

Treatment of Sympathomimetic Induced Intraventricular Hemorrhage with Intraventricular Urokinase

Wendy C. Ziai, Antigone Triantaphyllopoulou, Alexander Y. Razumovsky, Daniel F. Hanley

School of Medicine

Research output: Contribution to journal › Article

Abstract

Intraventricular hemorrhage (IVH) occurred in a 32-year-old man following the use of both ephedrine and pseudoephedrine. Cerebral angiography and transcranial Doppler studies showed changes suggestive of vasculitis. We describe the management and investigations of a unique case of IVH. This patient was treated with ventriculostomy and intraventricular urokinase (UK). A favorable outcome was obtained with independent function at 10 weeks post hemorrhage. The use of intraventricular thrombolysis for drug-induced IVH has not previously been reported, although it has been shown to be a safe and potentially beneficial intervention.

Original language	English (US)
Pages (from-to)	276-279
Number of pages	4
Journal	Journal of Stroke and Cerebrovascular Diseases
Volume	12
Issue number	6
DOIs	https://doi.org/10.1016/j.jstrokecerebrovasdis.2003.09.011
State	Published - Jan 1 2003

Keywords

Intraventricular hemorrhage
Sympathomimetics
Thrombolysis
Urokinase

ASJC Scopus subject areas

Surgery
Rehabilitation
Clinical Neurology
Cardiology and Cardiovascular Medicine

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10.1016/j.jstrokecerebrovasdis.2003.09.011

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Ziai, W. C., Triantaphyllopoulou, A., Razumovsky, A. Y., & Hanley, D. F. (2003). Treatment of Sympathomimetic Induced Intraventricular Hemorrhage with Intraventricular Urokinase. Journal of Stroke and Cerebrovascular Diseases, 12(6), 276-279. https://doi.org/10.1016/j.jstrokecerebrovasdis.2003.09.011

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