TY - JOUR
T1 - Treatment of pertussis with pertussis immune globulin
AU - Balagtas, Rolando C.
AU - Nelson, Kenrad E.
AU - Levin, Stuart
AU - Gotoff, Samuel P.
PY - 1971/8
Y1 - 1971/8
N2 - Children with pertussis were treated with 2.5 c.c. of pertussis immune globulin or placebo in double-blind fashion. Patients were generally in the first week of the paroxysmal stage, and treatment and control groups were comparable. All children received ampicillin for 10 days. No difference in the rate of recovery between treated and control groups was noted with respect to the frequency of paroxysms of coughing, whooping, episodes of vomiting and suctioning required and pulmonary complications. These results are consistent with those of the few controlled studies in the literature, namely, that pertussis immune globulin is of no value in treatment at this stage of pertussis.
AB - Children with pertussis were treated with 2.5 c.c. of pertussis immune globulin or placebo in double-blind fashion. Patients were generally in the first week of the paroxysmal stage, and treatment and control groups were comparable. All children received ampicillin for 10 days. No difference in the rate of recovery between treated and control groups was noted with respect to the frequency of paroxysms of coughing, whooping, episodes of vomiting and suctioning required and pulmonary complications. These results are consistent with those of the few controlled studies in the literature, namely, that pertussis immune globulin is of no value in treatment at this stage of pertussis.
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U2 - 10.1016/S0022-3476(71)80102-6
DO - 10.1016/S0022-3476(71)80102-6
M3 - Article
C2 - 4104454
AN - SCOPUS:0015107693
SN - 0022-3476
VL - 79
SP - 203
EP - 208
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 2
ER -