Treatment of Pediatric IgG4-Related Orbital Disease With TNF-α Inhibitor

Sanjai Jalaj, Kristen Dunbar, Ashley Campbell, Michael Kazim

Research output: Contribution to journalArticle


The authors describe a 9-year-old female who presented with swelling, proptosis, and tenderness of the right upper eyelid and MRI imaging demonstrating right lacrimal gland enlargement. After failing treatment with corticosteroids, the patient underwent a biopsy that was consistent with IgG4-related orbital disease. She was subsequently successfully treated with adalimumab (TNF-α inhibitor). This is the first case report of the successful use of a TNF-α inhibitor for the treatment of IgG4-related orbital disease in a child.

Original languageEnglish (US)
JournalOphthalmic Plastic and Reconstructive Surgery
StateAccepted/In press - Jul 10 2017
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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