Treatment of Pediatric IgG4-Related Orbital Disease with TNF-α Inhibitor

Sanjai Jalaj, Kristen Dunbar, Ashley Campbell, Michael Kazim

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The authors describe a 9-year-old female who presented with swelling, proptosis, and tenderness of the right upper eyelid and MRI imaging demonstrating right lacrimal gland enlargement. After failing treatment with corticosteroids, the patient underwent a biopsy that was consistent with IgG4-related orbital disease. She was subsequently successfully treated with adalimumab (TNF-α inhibitor). This is the first case report of the successful use of a TNF-α inhibitor for the treatment of IgG4-related orbital disease in a child.

Original languageEnglish (US)
Pages (from-to)e10-e12
JournalOphthalmic plastic and reconstructive surgery
Issue number1
StatePublished - 2018
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


Dive into the research topics of 'Treatment of Pediatric IgG4-Related Orbital Disease with TNF-α Inhibitor'. Together they form a unique fingerprint.

Cite this