Treatment of Hepatoblastoma with Drug-eluting Bead Transarterial Chemoembolization in a 13-Month-Old Infant: A Case Report and Review of the Literature

Matthew Hoyer, Rakesh Goli, Katherine K. Barnett, Eric H. Raabe, Kelvin Hong

Research output: Contribution to journalArticle

Abstract

Background: Prior reports have shown the utility of conventional lipiodol-based transarterial chemoembolization in hepatoblastoma. The authors describe the first reported case of hepatoblastoma treated with drug-eluting bead transarterial chemoembolization (DEB-TACE). Observations: An 11-month-old infant presented with hepatoblastoma measuring 14.3 cm. A trial of cisplatin chemotherapy followed by sequential DEB-TACE to the tumor's feeding vasculature reduced the mass to 5.3 cm. The patient tolerated both sessions of DEB-TACE without any major complication. Having demonstrated adequate disease control, the patient then underwent successful liver transplantation. Conclusion: This report provides promising evidence for the treatment of hepatoblastoma with DEB-TACE.

Original languageEnglish (US)
JournalJournal of Pediatric Hematology/Oncology
DOIs
StateAccepted/In press - 2020

Keywords

  • DEB-TACE
  • hepatoblastoma
  • interventional oncology
  • interventional radiology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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