Treatment of epilepsy: The ketogenic diet

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Until the 20th century there were few effective treatments for epilepsy. Prayer and fasting had been advocated as therapy since at least biblical times. In the early 20th century attention turned to the fasting component and led to Wilder’s original publication in 1921 that outlined a ketogenic diet.1 On the basis of earlier studies of metabolism in diabetics, he recognized that fasting produced ketosis, which could be sustained by a diet that contained an excess of ketogenic foods (fats) rather than antiketogenic foods (proteins and carbohydrates). He and colleagues at the Mayo Clinic recommended an energyrestricted diet that provided approximately 1 g/kg per day of protein, a small amount of carbohydrates and more than 90 per cent of energy intake as fats.2.

Original languageEnglish (US)
Title of host publicationEpilepsy in Children, 2E
PublisherCRC Press
Number of pages4
ISBN (Electronic)9781444114089
ISBN (Print)9780340808146
StatePublished - Jan 1 2004

ASJC Scopus subject areas

  • Medicine(all)


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