Treatment of dyskeratosis congenita with granulocyte colony-stimulating factor and erythropoietin

Blanche P. Alter, Frank H. Gardner, Robert E. Hall

Research output: Contribution to journalArticle

Abstract

Aplastic anaemia is both frequent and difficult to manage in patients with dyskeratosis congenita (DC). We recently treated a 23-year-old male for a year with granulocyte colony-stimulating factor (G-CSF) and erythropoietin (Ep), with an excellent neutrophil response, and a transient effect on haemoglobin levels. G-CSF alone or combined with other cytokines may provide at least a partial effect in pancytopenic patients with DC.

Original languageEnglish (US)
Pages (from-to)309-311
Number of pages3
JournalBritish Journal of Haematology
Volume97
Issue number2
Publication statusPublished - 1997
Externally publishedYes

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Keywords

  • aplastic anaemia
  • dyskeratosis congenita
  • erythropoietin
  • G-CSF

ASJC Scopus subject areas

  • Hematology

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