TY - JOUR
T1 - Treatment of diazepam withdrawal syndrome with propranolol
AU - Abernethy, D. R.
AU - Greenblatt, D. J.
AU - Shader, R. I.
PY - 1981
Y1 - 1981
N2 - True physiologic addiction to diazepam has been reliably described in isolated cases by documentation of a physical withdrawal syndrome characterized by agitation, tachycardia, and diaphoresis and, rarely, hallucinations, psychosis, and seizures. Although usually occurring after prolonged use of high doses, in one case a withdrawal syndrome occuured after abrupt withdrawal of diazepam after long-term use in a usual therapeutic dose. The present report describes a case of diazepam withdrawal syndrome after long-term ingestion of extremely high doses. The case was documented and the patient effectively treated with propranolol.
AB - True physiologic addiction to diazepam has been reliably described in isolated cases by documentation of a physical withdrawal syndrome characterized by agitation, tachycardia, and diaphoresis and, rarely, hallucinations, psychosis, and seizures. Although usually occurring after prolonged use of high doses, in one case a withdrawal syndrome occuured after abrupt withdrawal of diazepam after long-term use in a usual therapeutic dose. The present report describes a case of diazepam withdrawal syndrome after long-term ingestion of extremely high doses. The case was documented and the patient effectively treated with propranolol.
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U2 - 10.7326/0003-4819-94-3-354
DO - 10.7326/0003-4819-94-3-354
M3 - Article
C2 - 7224383
AN - SCOPUS:0019524272
SN - 0003-4819
VL - 94
SP - 354
EP - 355
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 3
ER -