Treatment of complications after breast-conservation therapy

Deborah Frassica, Gopal K. Bajaj, Theodore N. Tsangaris

Research output: Contribution to journalArticle

Abstract

Over the past 2 decades, breast-conservation therapy with lumpectomy and whole-breast radiotherapy has become a standard option for the maJority of women with newly diagnosed breast cancer. Long-term local control is achieved in approximately 85% of patients, and the therapy is generally well tolerated. There can, however, be long-term effects on the breast and other nearby tissues that may range from asymptomatic findings on examination to severe, debilitating problems. Infection, fat necrosis, and severe musculoskeletal problems such as osteoradionecrosis or soft-tissue necrosis are uncommon, affecting less than 5% of patients. However, changes in range of motion, mild-to-moderate musculoskeletal pain, and arm and breast edema are much more common. As more women choose breast-conservation therapy for management of their breast cancer, physicians will encounter these problems, as well as in breast tumor recurrence, with greater frequency. This review will focus on the incidence, contributing factors, and management of the late problems of infection, fat necrosis, musculoskeletal complications, and local recurrence following breast-conservation therapy.

Original languageEnglish (US)
Pages (from-to)1118-1128
Number of pages11
JournalOncology
Volume17
Issue number8
StatePublished - Aug 2003

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Segmental Mastectomy
Fat Necrosis
Breast
Breast Neoplasms
Osteoradionecrosis
Recurrence
Musculoskeletal Pain
Therapeutics
Articular Range of Motion
Infection
Edema
Arm
Necrosis
Radiotherapy
Physicians
Incidence

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Frassica, D., Bajaj, G. K., & Tsangaris, T. N. (2003). Treatment of complications after breast-conservation therapy. Oncology, 17(8), 1118-1128.

Treatment of complications after breast-conservation therapy. / Frassica, Deborah; Bajaj, Gopal K.; Tsangaris, Theodore N.

In: Oncology, Vol. 17, No. 8, 08.2003, p. 1118-1128.

Research output: Contribution to journalArticle

Frassica, D, Bajaj, GK & Tsangaris, TN 2003, 'Treatment of complications after breast-conservation therapy', Oncology, vol. 17, no. 8, pp. 1118-1128.
Frassica D, Bajaj GK, Tsangaris TN. Treatment of complications after breast-conservation therapy. Oncology. 2003 Aug;17(8):1118-1128.
Frassica, Deborah ; Bajaj, Gopal K. ; Tsangaris, Theodore N. / Treatment of complications after breast-conservation therapy. In: Oncology. 2003 ; Vol. 17, No. 8. pp. 1118-1128.
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