TY - JOUR
T1 - Treatment of chronic inflammatory demyelinating polyneuropathy with cyclosporin-A
AU - Mahattanakul, Wattana
AU - Crawford, Thomas O.
AU - Griffin, John W.
AU - Goldstein, Jonathan M.
AU - Cornblath, David R.
PY - 1996/2
Y1 - 1996/2
N2 - Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated polyneuropathy for which there are effective therapies. However, not all patients improve with these treatments. Eight patients with CIDP, two with IgG monoclonal gammopathies, were treated with cyclosporin-A (3 to 5 mg/kg/day). In three, this treatment was successful. It was unsuccessful in four patients who were resistant to other treatments and in one who had initially received cyclosporin-A. There were no serious side effects. In selected patients with CIDP, cyclosporin-A is a potentially useful treatment.
AB - Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated polyneuropathy for which there are effective therapies. However, not all patients improve with these treatments. Eight patients with CIDP, two with IgG monoclonal gammopathies, were treated with cyclosporin-A (3 to 5 mg/kg/day). In three, this treatment was successful. It was unsuccessful in four patients who were resistant to other treatments and in one who had initially received cyclosporin-A. There were no serious side effects. In selected patients with CIDP, cyclosporin-A is a potentially useful treatment.
KW - Cyclosporin-A
KW - Inflammatory demyelinating polyneuropathy
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U2 - 10.1136/jnnp.60.2.185
DO - 10.1136/jnnp.60.2.185
M3 - Article
C2 - 8708650
AN - SCOPUS:0030063615
SN - 0022-3050
VL - 60
SP - 185
EP - 187
JO - Journal of Neurology Neurosurgery and Psychiatry
JF - Journal of Neurology Neurosurgery and Psychiatry
IS - 2
ER -