Treatment of benign cephalic histiocytosis with topical 1% rapamycin ointment

Kaiane Habeshian, Robert A. Silverman, Cynthia M.C. DeKlotz

Research output: Contribution to journalArticle


We report a pediatric case of extensive, progressive benign cephalic histiocytosis (BCH) involving the face, trunk, and extremities with response of facial lesions to treatment with topical 1% rapamycin. A split-face model was used to demonstrate improvement on the treated side versus the untreated side. After physician and parental perception of effectiveness, based in part on photodocumentation, subsequently both cheeks were treated with continued improvement.

Original languageEnglish (US)
Pages (from-to)411-413
Number of pages3
JournalPediatric Dermatology
Issue number3
StatePublished - May 1 2019


  • histiocytic disorders
  • neoplasms-benign
  • therapy-topical

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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