Treatment of acute neuropsychiatric lupus with intravenous immunoglobulin (IVIG): A case report and review of the literature

Aaron M. Milstone, Kevin Meyers, Josephine Elia

Research output: Contribution to journalArticle

Abstract

Neuropsychiatric lupus can be difficult to diagnose, and little prospective data exists to help direct management. In this case report we describe the acute onset of symptoms of depression, mania, and psychosis and their complete resolution 48 h following a 5-day treatment course of intravenous immunoglobulin (IVIG) in a 20-year-old woman with systemic lupus erythematosus (SLE). We review the literature on IVIG for the management of neuropsychiatric lupus. We propose that when more toxic therapies are refused or symptoms do not remit with other treatments, IVIG should be considered in patients with neuropsychiatric lupus.

Original languageEnglish (US)
Pages (from-to)394-397
Number of pages4
JournalClinical rheumatology
Volume24
Issue number4
DOIs
StatePublished - Aug 1 2005

Keywords

  • Autoantibodies
  • Intravenous immunoglobulin (IVIG)
  • Neuropsychiatric lupus
  • Systemic lupus erythematosus (SLE)

ASJC Scopus subject areas

  • Rheumatology

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