Treatment of 213 patients with symptomatic tarlov cysts by ct-guided percutaneous injection of fibrin sealant

K. Murphy, A. L. Oaklander, G. Elias, S. Kathuria, D. M. Long

Research output: Contribution to journalArticle

Abstract

Background and Purpose: There has been a steady progression of case reports and a small surgical series that report successful surgical treatment of Tarlov cysts with concomitant relief of patients' symptoms and improvement in their neurological dysfunction, yet patients are still told that these lesions are asymptomatic by physicians. The purpose of this study was to analyze the efficacy and safety of intervention in 213 consecutive patients with symptomatic Tarlov cysts treated by CT-guided 2-needle cyst aspiration and fibrin sealing. Materials and Methods: This study was designed to assess outcomes in patients who underwent CT-guided aspiration and injection of=1 sacral Tarlov cyst at Johns Hopkins Hospital between 2003 and 2013. In all, 289 cysts were treated in 213 consecutive patients. All these patients were followed for at least 6 months, 90% were followed for 1 year, and 83% were followed for 3-6 years. The aspiration-injection procedure used 2 needles and was performed with the patients under local anesthesia and intravenous anesthesia. In the fibrin-injection stage of the procedure, a commercially available fibrin sealant was injected into the cyst through the deep needle (Tisseel VH). RESULTS: One year postprocedure, excellent results were obtained in 104 patients (54.2% of patients followed), and good or satisfactory results were obtained in 53 patients (27.6%). Thus, 157 patients (81.8%) in all were initially satisfied with the outcome of treatment. At 3-6 years postprocedure, 74.0% of patients followed were satisfied with treatment. There were no clinically significant complications. Conclusions: The aspiration-injection technique described herein constitutes a safe and efficacious treatment option that holds promise for relieving cyst-related symptoms in many patients with very little risk.

Original languageEnglish (US)
Pages (from-to)373-379
Number of pages7
JournalAmerican Journal of Neuroradiology
Volume37
Issue number2
DOIs
StatePublished - Feb 1 2016

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Tarlov Cysts
Fibrin Tissue Adhesive
Injections
Cysts
Therapeutics
Needles
Fibrin
Intravenous Anesthesia

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

Cite this

Treatment of 213 patients with symptomatic tarlov cysts by ct-guided percutaneous injection of fibrin sealant. / Murphy, K.; Oaklander, A. L.; Elias, G.; Kathuria, S.; Long, D. M.

In: American Journal of Neuroradiology, Vol. 37, No. 2, 01.02.2016, p. 373-379.

Research output: Contribution to journalArticle

Murphy, K. ; Oaklander, A. L. ; Elias, G. ; Kathuria, S. ; Long, D. M. / Treatment of 213 patients with symptomatic tarlov cysts by ct-guided percutaneous injection of fibrin sealant. In: American Journal of Neuroradiology. 2016 ; Vol. 37, No. 2. pp. 373-379.
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