TY - JOUR
T1 - Treating acute pain in light of the chronification of pain
AU - Pergolizzi, Joseph V.
AU - Raffa, Robert B.
AU - Taylor, Robert
PY - 2014/3
Y1 - 2014/3
N2 - The progression of acute to chronic pain, also known as pain chronification, remains incompletely understood. Biologic factors involved in this transition include central sensitization, neuroplastic changes, altered pain modulation, and changes to the "neuromatrix." Chronic pain may involve irreversible pathophysiologic changes, so interrupting the cascade of events that allows acute pain to advance to chronic pain is of crucial importance. This involves recognition and prompt treatment of acute pain, better awareness and application of evidence-based guidelines on pain management by all clinicians (not just pain specialists), and patient education. By interrupting nociceptive input in acute pain conditions, it might be possible to prevent transition to chronic pain syndromes.
AB - The progression of acute to chronic pain, also known as pain chronification, remains incompletely understood. Biologic factors involved in this transition include central sensitization, neuroplastic changes, altered pain modulation, and changes to the "neuromatrix." Chronic pain may involve irreversible pathophysiologic changes, so interrupting the cascade of events that allows acute pain to advance to chronic pain is of crucial importance. This involves recognition and prompt treatment of acute pain, better awareness and application of evidence-based guidelines on pain management by all clinicians (not just pain specialists), and patient education. By interrupting nociceptive input in acute pain conditions, it might be possible to prevent transition to chronic pain syndromes.
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U2 - 10.1016/j.pmn.2012.07.004
DO - 10.1016/j.pmn.2012.07.004
M3 - Article
C2 - 24602441
AN - SCOPUS:84895133192
SN - 1524-9042
VL - 15
SP - 380
EP - 390
JO - Pain Management Nursing
JF - Pain Management Nursing
IS - 1
ER -