Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: A randomized, controlled trial

Richard F. Macko, Frederick M. Ivey, Larry W. Forrester, Daniel F Hanley, John D. Sorkin, Leslie I. Katzel, Kenneth Silver, Andrew P. Goldberg

Research output: Contribution to journalArticle

Abstract

Background and Purpose - Physical inactivity propagates disability after stroke through physical deconditioning and learned nonuse. We investigated whether treadmill aerobic training (T-AEX) is more effective than conventional rehabilitation to improve ambulatory function and cardiovascular fitness in patients with chronic stroke. Methods - Sixty-one adults with chronic hemiparetic gait after ischemic stroke (>6 months) were randomized to 6 months (3×/week) progressive T-AEX or a reference rehabilitation program of stretching plus low-intensity walking (R-CONTROL). Peak exercise capacity (Vo 2 peak), o 2 consumption during submaximal effort walking (economy of gait), timed walks, Walking Impairment Questionnaire (WIQ), and Rivermead Mobility Index (RMI) were measured before and after 3 and 6 months of training. Results - Twenty-five patients completed T-AEX and 20 completed R-CONTROL. Only T-AEX increased cardiovascular fitness (17% versus 3%, δ% T-AEX versus R-CONTROL, P2 peak (r=0.43, P

Original languageEnglish (US)
Pages (from-to)2206-2211
Number of pages6
JournalStroke
Volume36
Issue number10
DOIs
StatePublished - Oct 2005

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Exercise Therapy
Walking
Randomized Controlled Trials
Stroke
Gait
Rehabilitation
Exercise

Keywords

  • Exercise
  • Hemiplegia
  • Rehabilitation
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke : A randomized, controlled trial. / Macko, Richard F.; Ivey, Frederick M.; Forrester, Larry W.; Hanley, Daniel F; Sorkin, John D.; Katzel, Leslie I.; Silver, Kenneth; Goldberg, Andrew P.

In: Stroke, Vol. 36, No. 10, 10.2005, p. 2206-2211.

Research output: Contribution to journalArticle

Macko, Richard F. ; Ivey, Frederick M. ; Forrester, Larry W. ; Hanley, Daniel F ; Sorkin, John D. ; Katzel, Leslie I. ; Silver, Kenneth ; Goldberg, Andrew P. / Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke : A randomized, controlled trial. In: Stroke. 2005 ; Vol. 36, No. 10. pp. 2206-2211.
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