Traumatic Retinopathy in Primates: The Explanation of Commotio Retinae

Jack O. Sipperley, Harry A. Quigley, J. Donald M. Gass

Research output: Contribution to journalArticlepeer-review

Abstract

We have produced experimental commotio retinae in 12 owl monkeys by blunt trauma. The ophthalmoscopic and fluorescein angiographic appearance of this contrecoup lesion is identical to the acute traumatic retinal opacity in humans. We examined these eyes by light and electron microscopy from 4 hours to 12 weeks after injury. Immediately after injury, the only abnormality is disruption of the receptor outer segments. From one to six days after trauma, many receptor cells undergo degeneration. The retinal pigment epithelium phagocytoses the degenerating outer segments, occasionally migrating into the retina. There is no extracellular retinal edema. The opacity of commotio retinae seems to represent disrupted receptor cells. Visual loss may result from permanent loss of receptors. The pigment epithelial response to traumatic receptor damage is similar to that observed in experimental retinal detachment and light-induced retinal damage.

Original languageEnglish (US)
Pages (from-to)2267-2273
Number of pages7
JournalArchives of ophthalmology
Volume96
Issue number12
DOIs
StatePublished - Dec 1978

Keywords

  • Commotio retinae
  • ocular trauma
  • photoreceptor
  • retinal edema
  • retinal pigment epithelial cell migration

ASJC Scopus subject areas

  • Ophthalmology

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