Traumatic brain injuries: Predictive usefulness of CT

Daniel K. Kido, Christopher Cox, Robert W. Hamill, Barbara M. Rothenberg, Paul D. Woolf

Research output: Contribution to journalArticle


The computed tomographic (CT) scans from 72 patients with traumatic brain injury were reviewed to determine whether a specific type, location, or size of lesion correlated with changes in neurologic function (assessed with the Glasgow Coma Scale [GCS]), patient outcome (assessed with the Glasgow Outcome Scale [GOS]), or catecholamine levels. The lesions were classified as focal or diffuse. GOS changed as a function of lesion size (P = .00004) in the 48 patients with focal hemorrhages, regardless of whether the lesions were intra- or extraaxial, and in the 19 patients with normal CT scans. Patients with lesions larger than 4,100 mm3 had a twofold greater risk of a poor outcome than patients with smaller lesions (100% vs 50%). Patients with normal CT scans were significantly more likely to have mild neurological dysfunction or none than patients with abnormal CT scans (P = .03), but lesion location, skull fracture, and pineal shift were not significant predictors of GCS or GOS scores. A positive relationship existed between lesion size and both plasma norepinephrine and epinephrine levels (P <.02); a significant relationship existed between lesion size and GCS score (P = .02).

Original languageEnglish (US)
Pages (from-to)777-781
Number of pages5
Issue number3
Publication statusPublished - Mar 1992
Externally publishedYes



  • Brain, CT, 10.1211
  • Brain, hemorrhage, 10.434
  • Brain, injuries, 10.434
  • Trauma, 10.434

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Kido, D. K., Cox, C., Hamill, R. W., Rothenberg, B. M., & Woolf, P. D. (1992). Traumatic brain injuries: Predictive usefulness of CT. Radiology, 182(3), 777-781.