Abstract
Transverse Myelitis (TM) is a clinical syndrome in which an immune-mediated process causes neural injury to the spinal cord, resulting in varying degrees of weakness, sensory alterations and autonomic dysfunction. TM may exist as part of a multi-focal CNS disease (e.g. MS), multi-systemic disease (e.g. systemic lupus erythematosus), or as an isolated, idiopathic entity. In this article, we will summarize recent classification and diagnostic schemes (1), which provide a framework for the acute management of patients with TM. Additionally, we will review current concepts on the natural history, immunopathogenesis and treatment strategies for patients with TM.
Original language | English (US) |
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Pages (from-to) | 1483-1499 |
Number of pages | 17 |
Journal | Frontiers in Bioscience |
Volume | 9 |
DOIs | |
State | Published - 2004 |
Keywords
- Interleukin-6
- Neuroimmunologic disorders
- Review
- Transverse myelitis
- Transverse myelopathy
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Immunology and Microbiology