TY - JOUR
T1 - Transplant social worker and donor financial assistance to increase living donor kidney transplants among African Americans
T2 - The TALKS Study, a randomized comparative effectiveness trial
AU - Boulware, L. Ebony
AU - Sudan, Debra L.
AU - Strigo, Tara S.
AU - Ephraim, Patti L.
AU - Davenport, Clemontina A.
AU - Pendergast, Jane F.
AU - Pounds, Iris
AU - Riley, Jennie A.
AU - Falkovic, Margaret
AU - Alkon, Aviel
AU - Hill-Briggs, Felicia
AU - Cabacungan, Ashley N.
AU - Barrett, Tyler M.
AU - Mohottige, Dinushika
AU - McElroy, Lisa
AU - Diamantidis, Clarissa J.
AU - Ellis, Matthew J.
N1 - Funding Information:
Drs. Boulware, Ellis, Sudan, and Ms. Strigo were supported by National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases [R01DK098759]. Dr. Davenport Pendergast was supported (in part) by Grant Number UL1TR002553 from the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health (NIH), and NIH Roadmap for Medical Research. We would like to thank each study participant for their involvement in the TALKS study.
Publisher Copyright:
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons
PY - 2021/6
Y1 - 2021/6
N2 - Lack of donors hinders living donor kidney transplantation (LDKT) for African Americans. We studied the effectiveness of a transplant social worker intervention (TALK SWI) alone or paired with living donor financial assistance to activate African Americans’ potential living kidney donors. African Americans (N = 300) on the transplant waiting list were randomly assigned to usual care; TALK SWI; or TALK SWI plus Living Donor Financial Assistance. We quantified differences in live kidney donor activation (composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) after 12 months. Participants’ mean age was 52 years, 56% were male, and 43% had annual household income less than $40,000. Most previously pursued LDKT. Participants were highly satisfied with TALK social workers, but they rarely utilized Financial Assistance. After 12 months, few (n = 39, 13%) participants had a new donor activation event (35 [12%] new donor inquiries; 17 [6%] new donor evaluations; 4 [1%] LDKT). There were no group differences in donor activation events (subdistribution hazard ratio [95% CI]: 1.09 [0.51–2.30] for TALK SWI and 0.92 [0.42–2.02] for TALK SWI plus Financial Assistance compared to Usual Care, p = 91). Alternative interventions to increase LDKT for African Americans on the waiting list may be needed. Trial registration: ClinicalTrials.gov (NCT02369354).
AB - Lack of donors hinders living donor kidney transplantation (LDKT) for African Americans. We studied the effectiveness of a transplant social worker intervention (TALK SWI) alone or paired with living donor financial assistance to activate African Americans’ potential living kidney donors. African Americans (N = 300) on the transplant waiting list were randomly assigned to usual care; TALK SWI; or TALK SWI plus Living Donor Financial Assistance. We quantified differences in live kidney donor activation (composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) after 12 months. Participants’ mean age was 52 years, 56% were male, and 43% had annual household income less than $40,000. Most previously pursued LDKT. Participants were highly satisfied with TALK social workers, but they rarely utilized Financial Assistance. After 12 months, few (n = 39, 13%) participants had a new donor activation event (35 [12%] new donor inquiries; 17 [6%] new donor evaluations; 4 [1%] LDKT). There were no group differences in donor activation events (subdistribution hazard ratio [95% CI]: 1.09 [0.51–2.30] for TALK SWI and 0.92 [0.42–2.02] for TALK SWI plus Financial Assistance compared to Usual Care, p = 91). Alternative interventions to increase LDKT for African Americans on the waiting list may be needed. Trial registration: ClinicalTrials.gov (NCT02369354).
KW - clinical research / practice
KW - education
KW - kidney disease
KW - kidney transplantation / nephrology
KW - kidney transplantation: living donor
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U2 - 10.1111/ajt.16403
DO - 10.1111/ajt.16403
M3 - Article
C2 - 33210831
AN - SCOPUS:85099211354
SN - 1600-6135
VL - 21
SP - 2175
EP - 2187
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 6
ER -