Transplant of SARS-CoV-2-infected Living Donor Liver: Case Report

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Abstract

Given the high community prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), transplant programs will encounter SARS-CoV-2 infections in living donors or recipients in the perioperative period. There is limited data on SARS-CoV-2 viremia and organotropism beyond the respiratory tract to inform the risk of transplant transmission of SARS-CoV-2. We report a case of a living donor liver transplant recipient who received a right lobe graft from a living donor with symptomatic PCR-confirmed SARS-CoV-2 infection 3 d following donation. The donor was successfully treated with remdesivir, dexamethasone, and coronavirus disease 2019 (COVID-19) convalescent plasma. No viral transmission was identified, and both donor and recipient had excellent postoperative outcomes.

Original languageEnglish (US)
Pages (from-to)E721
JournalTransplantation Direct
Volume7
Issue number8
DOIs
StatePublished - Jul 8 2021

ASJC Scopus subject areas

  • Transplantation

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