Transoral robotic surgery and a paradigm shift in the management of oropharyngeal squamous cell carcinoma

Harry Quon, Bert W. O'Malley, Gregory S. Weinstein

Research output: Contribution to journalReview article

Abstract

Efforts to improve upon oncologic results for resectable oropharyngeal carcinoma over the past 40 years have yielded many treatment options. However, the two fundamental approaches, surgical and nonsurgical, have not been compared in a randomized trial. Both approaches can be effective and both can cause treatment-related swallowing complications. Early experience combining technological advancements with conformal radiotherapy and transoral robotic surgery suggests that the risk of swallowing complications may be reduced and that treatment outcomes may be improved through pathologic stratification and risk-adapted adjuvant therapy. This may also be a valid strategy upon which treatment de-intensification may be studied for human-papillomavirus-associated oropharyngeal carcinoma due to its favorable prognosis.

Original languageEnglish (US)
Pages (from-to)79-86
Number of pages8
JournalJournal of Robotic Surgery
Volume4
Issue number2
DOIs
StatePublished - Jun 29 2010
Externally publishedYes

Keywords

  • Concurrent chemotherapy
  • Oropharynx carcinoma
  • Radiotherapy
  • Review
  • Risk stratification
  • Transoral robotic surgery
  • Treatment paradigm
  • Treatment-related swallowing complications

ASJC Scopus subject areas

  • Surgery
  • Health Informatics

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