Transient thyrotoxicosis in an infant delivered to a long-acting thyroid stimulator (lats)- and lats protector-negative, thyroid-stimulating antibody- positive woman with hashimoto’s thyroiditis

William H. Hoffman, Palghat Sahasrananan, Sisinio S. Ferandos, C. Lynne Burek, Noel R. Rose

Research output: Contribution to journalArticlepeer-review

Abstract

A thyrotoxic infant was delivered to a womanwith a long-standing history of Hashimoto’s thyroiditis, but withno evidence of Graves’ disease. Long-acting thyroid stimulator(LATS) and LATS protector were absent, but thyroid-stimulatingantibody was transiently present in the infant and markedlyand persistently elevated in the mother. It is concluded that the maternal level of thyroid-stimulating immunoglobulins determinesthe presence and duration of transient neonatal thyrotoxicosis, and that thyroid-stimulating antibody is distinct from LATS and LATS protector.

Original languageEnglish (US)
Pages (from-to)354-356
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume54
Issue number2
DOIs
StatePublished - Feb 1982

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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