Transient erythroblastopenia of childhood (TEC) presenting as leukoerythroblastic anemia

Ophard K. Mupanomunda, Blanche P. Alter

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The diagnosis of transient erythroblastopenia of childhood (TEC) is usually straightforward, with temporary cessation of red blood cell production resulting in normocytic normochromic anemia, reticulocytopenia, and bone marrow erythroblastopenia. We describe here a case of TEC presenting with features of leukoerythroblastic anemia. To our knowledge, this is the first such report for TEC. Patient and Methods: The case of a 1-year-old girl is described who had a leukoerythroblastic anemia. Bone marrow examination and clinical course indicated that the anemia had a benign etiology-TEC. Results: The patient presented with anemia, leukocytosis, and a left shift, with metamyelocytes, myelocytes, myeloblasts, and nucleated red cells in the circulation. There was no apparent viral etiology, and the bone marrow aspirate findings were consistent with a recovering marrow. After transfusion, the patient had an uneventful recovery from TEC. Conclusion: TEC can cause leukoerythroblastic anemia. TEC with this presentation is clinically similar to TEC without leukoerythroblastosis, but other causes of leukoerythroblastosis need to be excluded.

Original languageEnglish (US)
Pages (from-to)165-167
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume19
Issue number2
DOIs
StatePublished - Mar 1997
Externally publishedYes

Keywords

  • Leukoerythroblastic anemia
  • Nucleated red blood cells (nRBCs)
  • Transient erythroblastopenia of childhood (TEC)

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

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