Transient and reproducible loss of motor-evoked potential signals after intravenous levetiracetam in a child undergoing craniotomy for resection of astrocytoma

Allan F. Simpao, Luke S. Janik, Grace Hsu, Alan J.ay Schwartz, Gregory G. Heuer, Andrew P. Warrington, Mohamed A. Rehman

Research output: Contribution to journalArticlepeer-review

Abstract

Transcranial electrical motor-evoked potential (tceMEP) monitoring is used in complex intracranial and spinal surgeries to detect and prevent neurological injury. We present a case of transient, reproducible loss of tceMEPs after an infusion of levetiracetam during craniotomy and tumor resection in a child. Cessation of the infusion resulted in restoration of baseline tceMEPs. When the infusion was resumed at the end of the procedure, a similar decrease in tceMEPs was seen as before, after the infusion was stopped. The surgery and postoperative course proceeded without incident, and the patient experienced a full recovery.

Original languageEnglish (US)
Pages (from-to)26-28
Number of pages3
JournalA & A case reports
Volume4
Issue number2
DOIs
StatePublished - Jan 15 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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