Transient and reproducible loss of motor-evoked potential signals after intravenous levetiracetam in a child undergoing craniotomy for resection of astrocytoma

Allan F. Simpao; Luke S. Janik; Grace Hsu; Alan J.ay Schwartz; Gregory G. Heuer; Andrew P. Warrington; Mohamed A. Rehman

doi:10.1213/XAA.0000000000000107

Transient and reproducible loss of motor-evoked potential signals after intravenous levetiracetam in a child undergoing craniotomy for resection of astrocytoma

Allan F. Simpao, Luke S. Janik, Grace Hsu, Alan J.ay Schwartz, Gregory G. Heuer, Andrew P. Warrington, Mohamed A. Rehman

Research output: Contribution to journal › Article › peer-review

Abstract

Transcranial electrical motor-evoked potential (tceMEP) monitoring is used in complex intracranial and spinal surgeries to detect and prevent neurological injury. We present a case of transient, reproducible loss of tceMEPs after an infusion of levetiracetam during craniotomy and tumor resection in a child. Cessation of the infusion resulted in restoration of baseline tceMEPs. When the infusion was resumed at the end of the procedure, a similar decrease in tceMEPs was seen as before, after the infusion was stopped. The surgery and postoperative course proceeded without incident, and the patient experienced a full recovery.

Original language	English (US)
Pages (from-to)	26-28
Number of pages	3
Journal	A & A case reports
Volume	4
Issue number	2
DOIs	https://doi.org/10.1213/XAA.0000000000000107
State	Published - Jan 15 2015
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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Transient and reproducible loss of motor-evoked potential signals after intravenous levetiracetam in a child undergoing craniotomy for resection of astrocytoma. / Simpao, Allan F.; Janik, Luke S.; Hsu, Grace; Schwartz, Alan J.ay; Heuer, Gregory G.; Warrington, Andrew P.; Rehman, Mohamed A.

In: A & A case reports, Vol. 4, No. 2, 15.01.2015, p. 26-28.

Research output: Contribution to journal › Article › peer-review

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abstract = "Transcranial electrical motor-evoked potential (tceMEP) monitoring is used in complex intracranial and spinal surgeries to detect and prevent neurological injury. We present a case of transient, reproducible loss of tceMEPs after an infusion of levetiracetam during craniotomy and tumor resection in a child. Cessation of the infusion resulted in restoration of baseline tceMEPs. When the infusion was resumed at the end of the procedure, a similar decrease in tceMEPs was seen as before, after the infusion was stopped. The surgery and postoperative course proceeded without incident, and the patient experienced a full recovery. ",

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AU - Schwartz, Alan J.ay

AU - Heuer, Gregory G.

AU - Warrington, Andrew P.

AU - Rehman, Mohamed A.

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AB - Transcranial electrical motor-evoked potential (tceMEP) monitoring is used in complex intracranial and spinal surgeries to detect and prevent neurological injury. We present a case of transient, reproducible loss of tceMEPs after an infusion of levetiracetam during craniotomy and tumor resection in a child. Cessation of the infusion resulted in restoration of baseline tceMEPs. When the infusion was resumed at the end of the procedure, a similar decrease in tceMEPs was seen as before, after the infusion was stopped. The surgery and postoperative course proceeded without incident, and the patient experienced a full recovery.

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Transient and reproducible loss of motor-evoked potential signals after intravenous levetiracetam in a child undergoing craniotomy for resection of astrocytoma

Abstract

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