Transcriptional activation of adipogenesis

Zhidan Wu, Pere Puigserver, Bruce M. Spiegelman

Research output: Contribution to journalArticle

Abstract

Studies from the past several years have revealed that adipogenesis is controlled by an interplay of transcription factors, including members of the CCAAT/enhancer binding protein family and peroxisome proliferator activated receptor γ. In addition to providing a new understanding of this aspect of the energy balance systems, these factors provide potential new targets for therapeutic intervention in metabolic diseases, such as obesity and type 2 diabetes mellitus.

Original languageEnglish (US)
Pages (from-to)689-694
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume11
Issue number6
DOIs
StatePublished - Dec 1 1999
Externally publishedYes

Fingerprint

CCAAT-Enhancer-Binding Proteins
Adipogenesis
Peroxisome Proliferator-Activated Receptors
Metabolic Diseases
Type 2 Diabetes Mellitus
Transcriptional Activation
Transcription Factors
Obesity
Therapeutics

ASJC Scopus subject areas

  • Cell Biology

Cite this

Transcriptional activation of adipogenesis. / Wu, Zhidan; Puigserver, Pere; Spiegelman, Bruce M.

In: Current Opinion in Cell Biology, Vol. 11, No. 6, 01.12.1999, p. 689-694.

Research output: Contribution to journalArticle

Wu, Z, Puigserver, P & Spiegelman, BM 1999, 'Transcriptional activation of adipogenesis', Current Opinion in Cell Biology, vol. 11, no. 6, pp. 689-694. https://doi.org/10.1016/S0955-0674(99)00037-X
Wu, Zhidan ; Puigserver, Pere ; Spiegelman, Bruce M. / Transcriptional activation of adipogenesis. In: Current Opinion in Cell Biology. 1999 ; Vol. 11, No. 6. pp. 689-694.
@article{63fb0a7aa64a43be8d25f81b0c2cee66,
title = "Transcriptional activation of adipogenesis",
abstract = "Studies from the past several years have revealed that adipogenesis is controlled by an interplay of transcription factors, including members of the CCAAT/enhancer binding protein family and peroxisome proliferator activated receptor γ. In addition to providing a new understanding of this aspect of the energy balance systems, these factors provide potential new targets for therapeutic intervention in metabolic diseases, such as obesity and type 2 diabetes mellitus.",
author = "Zhidan Wu and Pere Puigserver and Spiegelman, {Bruce M.}",
year = "1999",
month = "12",
day = "1",
doi = "10.1016/S0955-0674(99)00037-X",
language = "English (US)",
volume = "11",
pages = "689--694",
journal = "Current Opinion in Cell Biology",
issn = "0955-0674",
publisher = "Elsevier Limited",
number = "6",

}

TY - JOUR

T1 - Transcriptional activation of adipogenesis

AU - Wu, Zhidan

AU - Puigserver, Pere

AU - Spiegelman, Bruce M.

PY - 1999/12/1

Y1 - 1999/12/1

N2 - Studies from the past several years have revealed that adipogenesis is controlled by an interplay of transcription factors, including members of the CCAAT/enhancer binding protein family and peroxisome proliferator activated receptor γ. In addition to providing a new understanding of this aspect of the energy balance systems, these factors provide potential new targets for therapeutic intervention in metabolic diseases, such as obesity and type 2 diabetes mellitus.

AB - Studies from the past several years have revealed that adipogenesis is controlled by an interplay of transcription factors, including members of the CCAAT/enhancer binding protein family and peroxisome proliferator activated receptor γ. In addition to providing a new understanding of this aspect of the energy balance systems, these factors provide potential new targets for therapeutic intervention in metabolic diseases, such as obesity and type 2 diabetes mellitus.

UR - http://www.scopus.com/inward/record.url?scp=0032727505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032727505&partnerID=8YFLogxK

U2 - 10.1016/S0955-0674(99)00037-X

DO - 10.1016/S0955-0674(99)00037-X

M3 - Article

C2 - 10600710

AN - SCOPUS:0032727505

VL - 11

SP - 689

EP - 694

JO - Current Opinion in Cell Biology

JF - Current Opinion in Cell Biology

SN - 0955-0674

IS - 6

ER -