TY - JOUR
T1 - Transcervical ultrasonography is feasible to visualize and evaluate base of tongue cancers
AU - Blanco, Ray Gervacio F.
AU - Califano, Joseph
AU - Messing, Barbara
AU - Richmon, Jeremy
AU - Liu, Jia
AU - Quon, Harry
AU - Neuner, Geoffrey
AU - Saunders, John
AU - Ha, Patrick K.
AU - Sheth, Sheila
AU - Gillison, Maura
AU - Fakhry, Carole
PY - 2014/1/30
Y1 - 2014/1/30
N2 - Background: Base of tongue (BOT) is a difficult subsite to examine clinically and radiographically. Yet, anatomic delineation of the primary tumor site, its extension to adjacent sites or across midline, and endophytic vs. exophytic extent are important characteristics for staging and treatment planning. We hypothesized that ultrasound could be used to visualize and describe BOT tumors. Methods: Transcervical ultrasound was performed using a standardized protocol in cases and controls. Cases had suspected or confirmed BOT malignancy. Controls were healthy individuals without known malignancy. Results: 100% of BOT tumors were visualized. On ultrasound BOT tumors were hypoechoic (90.9%) with irregular margins (95.5%). Ultrasound could be used to characterize adjacent site involvement, midline extent, and endophytic extent, and visualize the lingual artery. No tumors were suspected for controls. Conclusions: Ultrasonography can be used to transcervically visualize BOT tumors and provides clinically relevant characteristics that may not otherwise be appreciable.
AB - Background: Base of tongue (BOT) is a difficult subsite to examine clinically and radiographically. Yet, anatomic delineation of the primary tumor site, its extension to adjacent sites or across midline, and endophytic vs. exophytic extent are important characteristics for staging and treatment planning. We hypothesized that ultrasound could be used to visualize and describe BOT tumors. Methods: Transcervical ultrasound was performed using a standardized protocol in cases and controls. Cases had suspected or confirmed BOT malignancy. Controls were healthy individuals without known malignancy. Results: 100% of BOT tumors were visualized. On ultrasound BOT tumors were hypoechoic (90.9%) with irregular margins (95.5%). Ultrasound could be used to characterize adjacent site involvement, midline extent, and endophytic extent, and visualize the lingual artery. No tumors were suspected for controls. Conclusions: Ultrasonography can be used to transcervically visualize BOT tumors and provides clinically relevant characteristics that may not otherwise be appreciable.
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U2 - 10.1371/journal.pone.0087565
DO - 10.1371/journal.pone.0087565
M3 - Article
C2 - 24498138
AN - SCOPUS:84900387525
SN - 1932-6203
VL - 9
JO - PloS one
JF - PloS one
IS - 1
M1 - e87565
ER -