Tracking of stem cells in vivo for cardiovascular applications

Nicole Azene, Yingli Fu, Jeremy Maurer, Dara L. Kraitchman

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

In the past ten years, the concept of injecting stem and progenitor cells to assist with rebuilding damaged blood vessels and myocardial tissue after injury in the heart and peripheral vasculature has moved from bench to bedside. Non-invasive imaging can not only provide a means to assess cardiac repair and, thereby, cellular therapy efficacy but also a means to confirm cell delivery and engraftment after administration. In this first of a two-part review, we will review the different types of cellular labeling techniques and the application of these techniques in cardiovascular magnetic resonance and ultrasound. In addition, we provide a synopsis of the cardiac cellular clinical trials that have been performed to-date.

Original languageEnglish (US)
Article number7
JournalJournal of Cardiovascular Magnetic Resonance
Volume16
Issue number1
DOIs
StatePublished - Jan 10 2014

Keywords

  • Cardiovascular disease
  • Cardiovascular magnetic resonance
  • Cell labeling
  • Cell tracking
  • Computed tomography
  • Fluoroscopy
  • Image-guided therapy
  • Optical imaging
  • Radionuclide imaging
  • Stem cells
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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