Trachoma

Hugh R. Taylor, Matthew J. Burton, Danny Haddad, Sheila West, Heathcote Wright

Research output: Contribution to journalArticlepeer-review

Abstract

Trachoma is the most common infectious cause of blindness. Repeated episodes of infection with Chlamydia trachomatis in childhood lead to severe conjunctival inflammation, scarring, and potentially blinding inturned eyelashes (trichiasis or entropion) in later life. Trachoma occurs in resource-poor areas with inadequate hygiene, where children with unclean faces share infected ocular secretions. Much has been learnt about the epidemiology and pathophysiology of trachoma. Integrated control programmes are implementing the SAFE Strategy: surgery for trichiasis, mass distribution of antibiotics, promotion of facial cleanliness, and environmental improvement. This strategy has successfully eliminated trachoma in several countries and global efforts are underway to eliminate blinding trachoma worldwide by 2020.

Original languageEnglish (US)
Pages (from-to)2142-2152
Number of pages11
JournalThe Lancet
Volume384
Issue number9960
DOIs
StatePublished - Dec 13 2014

ASJC Scopus subject areas

  • Medicine(all)

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