Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient

R. A. Meyer, E. C. Hills, M. H. Friedman

Research output: Contribution to journalArticlepeer-review

Abstract

The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The difference can be explained if the membrane is heteroporous. Similar results are expected for other heterogeneous biological or artificial membranes.

Original languageEnglish (US)
Pages (from-to)247-253
Number of pages7
JournalJournal of Membrane Science
Volume8
Issue number3
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Biochemistry
  • Materials Science(all)
  • Physical and Theoretical Chemistry
  • Filtration and Separation

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