Toxoplasmic scleritis

J. S. Schuman, Robert S Weinberg, A. P. Ferry, R. K. Guerry

Research output: Contribution to journalArticle

Abstract

Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplasmosis. Their retinochoroiditis and scleritis responded well to medical therapy. Retinochoroiditis and scleritis that was refractory to treatment developed in the other three patients, two of whom had been receiving immunosuppressive therapy for systemic diseases. Their therapeutic regimens did not include treatment for toxoplasmosis. All three eyes became blind and were enucleated. Results of pathologic examination of all three enucleated eyes showed Toxoplasma gondii in the retina. There was severe inflammation of the retina, choroid, and sclera. Toxoplasmosis should be considered in the clinical differential diagnosis of scleritis associated with retinochoroiditis, particularly in immunosuppressed patients.

Original languageEnglish (US)
Pages (from-to)1399-1403
Number of pages5
JournalOphthalmology
Volume95
Issue number10
StatePublished - 1988
Externally publishedYes

Fingerprint

Scleritis
Toxoplasmosis
Retina
Inflammation
Therapeutics
Sclera
Choroid
Toxoplasma
Immunosuppressive Agents
Differential Diagnosis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Schuman, J. S., Weinberg, R. S., Ferry, A. P., & Guerry, R. K. (1988). Toxoplasmic scleritis. Ophthalmology, 95(10), 1399-1403.

Toxoplasmic scleritis. / Schuman, J. S.; Weinberg, Robert S; Ferry, A. P.; Guerry, R. K.

In: Ophthalmology, Vol. 95, No. 10, 1988, p. 1399-1403.

Research output: Contribution to journalArticle

Schuman, JS, Weinberg, RS, Ferry, AP & Guerry, RK 1988, 'Toxoplasmic scleritis', Ophthalmology, vol. 95, no. 10, pp. 1399-1403.
Schuman JS, Weinberg RS, Ferry AP, Guerry RK. Toxoplasmic scleritis. Ophthalmology. 1988;95(10):1399-1403.
Schuman, J. S. ; Weinberg, Robert S ; Ferry, A. P. ; Guerry, R. K. / Toxoplasmic scleritis. In: Ophthalmology. 1988 ; Vol. 95, No. 10. pp. 1399-1403.
@article{9d4ed0d89495447d905a3e1fd8a65d3e,
title = "Toxoplasmic scleritis",
abstract = "Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplasmosis. Their retinochoroiditis and scleritis responded well to medical therapy. Retinochoroiditis and scleritis that was refractory to treatment developed in the other three patients, two of whom had been receiving immunosuppressive therapy for systemic diseases. Their therapeutic regimens did not include treatment for toxoplasmosis. All three eyes became blind and were enucleated. Results of pathologic examination of all three enucleated eyes showed Toxoplasma gondii in the retina. There was severe inflammation of the retina, choroid, and sclera. Toxoplasmosis should be considered in the clinical differential diagnosis of scleritis associated with retinochoroiditis, particularly in immunosuppressed patients.",
author = "Schuman, {J. S.} and Weinberg, {Robert S} and Ferry, {A. P.} and Guerry, {R. K.}",
year = "1988",
language = "English (US)",
volume = "95",
pages = "1399--1403",
journal = "Ophthalmology",
issn = "0161-6420",
publisher = "Elsevier Inc.",
number = "10",

}

TY - JOUR

T1 - Toxoplasmic scleritis

AU - Schuman, J. S.

AU - Weinberg, Robert S

AU - Ferry, A. P.

AU - Guerry, R. K.

PY - 1988

Y1 - 1988

N2 - Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplasmosis. Their retinochoroiditis and scleritis responded well to medical therapy. Retinochoroiditis and scleritis that was refractory to treatment developed in the other three patients, two of whom had been receiving immunosuppressive therapy for systemic diseases. Their therapeutic regimens did not include treatment for toxoplasmosis. All three eyes became blind and were enucleated. Results of pathologic examination of all three enucleated eyes showed Toxoplasma gondii in the retina. There was severe inflammation of the retina, choroid, and sclera. Toxoplasmosis should be considered in the clinical differential diagnosis of scleritis associated with retinochoroiditis, particularly in immunosuppressed patients.

AB - Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplasmosis. Their retinochoroiditis and scleritis responded well to medical therapy. Retinochoroiditis and scleritis that was refractory to treatment developed in the other three patients, two of whom had been receiving immunosuppressive therapy for systemic diseases. Their therapeutic regimens did not include treatment for toxoplasmosis. All three eyes became blind and were enucleated. Results of pathologic examination of all three enucleated eyes showed Toxoplasma gondii in the retina. There was severe inflammation of the retina, choroid, and sclera. Toxoplasmosis should be considered in the clinical differential diagnosis of scleritis associated with retinochoroiditis, particularly in immunosuppressed patients.

UR - http://www.scopus.com/inward/record.url?scp=0023814813&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023814813&partnerID=8YFLogxK

M3 - Article

C2 - 3226688

AN - SCOPUS:0023814813

VL - 95

SP - 1399

EP - 1403

JO - Ophthalmology

JF - Ophthalmology

SN - 0161-6420

IS - 10

ER -