Abstract
Diarrhoea remains a common cause of illness in Guatemala, with children suffering most frequently from the disease. This study directly compared the frequency, enterotoxin, and colonization factor (CF) profiles of enterotoxigenic Escherichia coli (ETEC) strains isolated from children living in a rural community in Guatemala and from Western visitors to the same location during the same seasons, using similar detection methodologies. We found that ETEC accounted for 26% of severe cases of diarrhoea in children requiring hospitalization, 15% of diarrhoea in the community, and 29% of travellers' diarrhoea in visitors staying ≥2 weeks. The toxin and CF patterns of the ETEC strains isolated from both groups differed significantly (P < 0·0005) as determined by χ2 = 60·39 for CFs and χ2 = 35 for toxins, while ETEC phenotypes found in Guatemalan children were comparable to those found in children from other areas of the world.
Original language | English (US) |
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Pages (from-to) | 1662-1671 |
Number of pages | 10 |
Journal | Epidemiology and infection |
Volume | 143 |
Issue number | 8 |
DOIs | |
State | Published - Mar 15 2015 |
Keywords
- Diarrhoea
- Escherichia coli
- enteric bacteria
- enterotoxin
- travellers' infection
ASJC Scopus subject areas
- Epidemiology
- Infectious Diseases