Toxicity Testing in the 21st Century: Approaches to Implementation

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A number of activities have started to implement the 2007 National Research Council report on "Toxicity Testing in the 21st Century - A Vision and a Strategy." These activities aim to embrace modern technologies and base safety assessments on the mode of actions of toxicants. Molecularly defined pathways of toxicity are at the center of the approach, collectively forming the Human Toxome.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Toxicology
Subtitle of host publicationThird Edition
PublisherElsevier
Pages673-675
Number of pages3
ISBN (Electronic)9780123864543
ISBN (Print)9780123864550
DOIs
StatePublished - Jan 1 2014

Keywords

  • 3Rs
  • Alternative methods
  • Evidence-based toxicology
  • High-throughput testing
  • Human toxome
  • Omics technologies
  • Pathways of toxicity
  • Regulatory toxicology

ASJC Scopus subject areas

  • Medicine(all)

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