Toxic environmental exposures and kidney health in children

Research output: Contribution to journalArticle

Abstract

High-level exposures to a number of agents are known to have direct nephrotoxic effects in children. A growing body of literature supports the hypothesis that chronic, relatively low-level exposure to various nephrotoxicants may also increase the risk for chronic kidney disease (CKD) or accelerate its progression. In this review we highlight several environmental nephrotoxicants and their association with CKD in children and adolescents. We also discuss unique epidemiological challenges in the use of kidney biomarkers in environmental nephrotoxicology.

Original languageEnglish (US)
JournalPediatric Nephrology
DOIs
StateAccepted/In press - Oct 12 2015

Fingerprint

Poisons
Environmental Exposure
Chronic Renal Insufficiency
Kidney
Biomarkers
Child Health

Keywords

  • Aristolochic acid
  • Arsenic
  • Cadmium
  • Chronic kidney disease
  • Environmental nephrotoxicants
  • Lead
  • Melamine

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Toxic environmental exposures and kidney health in children. / Weidemann, Darcy K.; Weaver, Virginia Marie; Fadrowski, Jeffrey J.

In: Pediatric Nephrology, 12.10.2015.

Research output: Contribution to journalArticle

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