Towards intra-operative prostate brachytherapy dosimetry based on partial seed localization in ultrasound and registration to C-arm fluoroscopy

Mehdi Moradi, S. Sara Mahdavi, Sanchit Deshmukh, Julio Lobo, Ehsan Dehghan, Gabor Fichtinger, William J. Morris, Septimiu E. Salcudean

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Intraoperative dosimetry during prostate brachytherapy is a long standing clinical problem. We propose a novel framework to address this problem by reliable detection of a subset of seeds from 3D transrectal ultrasound and registration to fluoroscopy. Seed detection in ultrasound is achieved through template matching in the RF ultrasound domain followed by thresholding and spatial filtering based on the fixed distance between stranded seeds. This subset of seeds is registered to the complete reconstruction of the implant in C-arm fluoroscopy. We report results, validated with a leave-one-needle-out approach, both in a phantom (average post-registration seed distance of 2.5 mm) and in three clinical patient datasets (average error: 3.9 mm over 113 seeds).

Original languageEnglish (US)
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages291-298
Number of pages8
Volume6891 LNCS
EditionPART 1
DOIs
StatePublished - 2011
Externally publishedYes
Event14th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2011 - Toronto, ON, Canada
Duration: Sep 18 2011Sep 22 2011

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume6891 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other14th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2011
CountryCanada
CityToronto, ON
Period9/18/119/22/11

ASJC Scopus subject areas

  • Computer Science(all)
  • Theoretical Computer Science

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    Moradi, M., Sara Mahdavi, S., Deshmukh, S., Lobo, J., Dehghan, E., Fichtinger, G., Morris, W. J., & Salcudean, S. E. (2011). Towards intra-operative prostate brachytherapy dosimetry based on partial seed localization in ultrasound and registration to C-arm fluoroscopy. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (PART 1 ed., Vol. 6891 LNCS, pp. 291-298). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6891 LNCS, No. PART 1). https://doi.org/10.1007/978-3-642-23623-5_37