TY - GEN
T1 - TOWARDS A UNIVERSAL DEVICE FOR POINT-OF-CARE MEDICINE
T2 - 2022 Design of Medical Devices Conference, DMD 2022
AU - Abramson, Haley
AU - Curry, Eli
AU - Sampath, Kaushik
AU - Wissman, James
AU - Mess, Griffin
AU - Thombre, Rasika
AU - Mahapatra, Smruti
AU - Aghabaglou, Fariba
AU - Theodore, Nicholas
AU - Pustavoitau, Aliaksei
AU - Manbachi, Amir
N1 - Funding Information:
The authors would like to thank the National Science Foundation Graduate Research Fellowship, Defense Advanced Research Projects Agency, DARPA, Award Contract #: N660012024075, and the Stimulating and Advancing ACCM Research, StAAR, Transformative award from the Department of Anesthesiology and Critical Care Medicine and Johns Hopkins School of Medicine. The authors would also like to thank Richard Mejia for his assistance and supervision in equipment management.
Publisher Copyright:
© 2022 by ASME
PY - 2022
Y1 - 2022
N2 - Universalized point-of-care medicine demands long-term, automated, and ubiquitous solutions to monitoring patients. Ultrasound imaging can be found in nearly all fields of healthcare. Therefore, developing a platform for continuous ultrasound acquisition could transform the point-of-care arena. However, long-term monitoring using ultrasound imaging requires both the simplification of large quantities of data and a hands-free, flexible device. Here, we reduce data-heavy spectral Doppler imaging by tracking local vascular flow in vitro and in vivo as a single, clinically interpretable value over time. Imaging is performed using a novel probe designed specifically for continuous monitoring with ultrasound. This semi-conformal specialty probe was fabricated by removing the plastic casing of a commercially available probe, bending the tip of the piezoelectric transducer head at a nearly ninety-degree angle, then casting the electronic components in silicone rubber, which allowed the probe to rest comfortably on any surface. No statistically significant difference existed when comparing the Doppler fluid velocity detected by the specialty probe with two commercial probes, where velocity directly leads to calculation of vascular flow. Additionally, continuously tracked velocity over the period of an hour and during periods of fluctuating flow rates demonstrated the potential for accurate, long-term monitoring using this ultrasound device. Thus, translating this technology from bench to bedside could provide a universal solution to point-of-care medicine.
AB - Universalized point-of-care medicine demands long-term, automated, and ubiquitous solutions to monitoring patients. Ultrasound imaging can be found in nearly all fields of healthcare. Therefore, developing a platform for continuous ultrasound acquisition could transform the point-of-care arena. However, long-term monitoring using ultrasound imaging requires both the simplification of large quantities of data and a hands-free, flexible device. Here, we reduce data-heavy spectral Doppler imaging by tracking local vascular flow in vitro and in vivo as a single, clinically interpretable value over time. Imaging is performed using a novel probe designed specifically for continuous monitoring with ultrasound. This semi-conformal specialty probe was fabricated by removing the plastic casing of a commercially available probe, bending the tip of the piezoelectric transducer head at a nearly ninety-degree angle, then casting the electronic components in silicone rubber, which allowed the probe to rest comfortably on any surface. No statistically significant difference existed when comparing the Doppler fluid velocity detected by the specialty probe with two commercial probes, where velocity directly leads to calculation of vascular flow. Additionally, continuously tracked velocity over the period of an hour and during periods of fluctuating flow rates demonstrated the potential for accurate, long-term monitoring using this ultrasound device. Thus, translating this technology from bench to bedside could provide a universal solution to point-of-care medicine.
KW - cardiac output
KW - continuous monitoring
KW - probe
KW - spectral Doppler imaging
KW - ultrasound
KW - vascular flow
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U2 - 10.1115/DMD2022-1006
DO - 10.1115/DMD2022-1006
M3 - Conference contribution
AN - SCOPUS:85130257111
T3 - Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022
BT - Proceedings of the 2022 Design of Medical Devices Conference, DMD 2022
PB - American Society of Mechanical Engineers
Y2 - 11 April 2022 through 14 April 2022
ER -