### Abstract

Coronary artery imaging with multi-slice helical computed tomography is a promising noninvasive imaging technique. The current major issues include the insufficient temporal resolution and large patient dose. We propose an image reconstruction method which provides a solution to both of the problems. The method uses an iterative approach repeating the following four steps until the difference between the two projection data sets falls below a certain criteria in step-4: 1) estimating or updating the cardiac motion vectors, 2) reconstructing the time-resolved 4D dynamic volume images using the motion vectors, 3) calculating the projection data from the current 4D images, 4) comparing them with the measured ones. In this study, we obtain the first estimate of the motion vector. We use the 4D NCAT phantom, a realistic computer model for the human anatomy and cardiac motions, to generate the dynamic fan-beam projection data sets as well to provide a known truth for the motion. Then, the halfscan reconstruction with the sliding time-window technique is used to generate cine images: f(t, r). Here, we use one heart beat for each position r so that the time information is retained. Next, the magnitude of the first derivative of f(t, r) with respect to time, i.e., |df/dt|, is calculated and summed over a region-of-interest (ROI), which is called the mean-absolute difference (MAD). The initial estimation of the vector field are obtained using MAD for each ROI. Results of the preliminary study are presented.

Original language | English (US) |
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Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |

Volume | 6142 I |

DOIs | |

State | Published - 2006 |

Event | Medical Imaging 2006: Physics of Medical Imaging - San Diego, CA, United States Duration: Feb 12 2006 → Feb 16 2006 |

### Other

Other | Medical Imaging 2006: Physics of Medical Imaging |
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Country | United States |

City | San Diego, CA |

Period | 2/12/06 → 2/16/06 |

### Fingerprint

### Keywords

- Cardiac CT
- Computed tomography (CT)
- Radiation dose
- Temporal resolution

### ASJC Scopus subject areas

- Engineering(all)

### Cite this

*Progress in Biomedical Optics and Imaging - Proceedings of SPIE*(Vol. 6142 I). [61420J] https://doi.org/10.1117/12.653279

**Toward time resolved 4D cardiac CT imaging with patient dose reduction; estimating the global heart motion.** / Taguchi, Katsuyuki; Segars, W. Paul; Fung, George S K; Tsui, Benjamin.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Progress in Biomedical Optics and Imaging - Proceedings of SPIE.*vol. 6142 I, 61420J, Medical Imaging 2006: Physics of Medical Imaging, San Diego, CA, United States, 2/12/06. https://doi.org/10.1117/12.653279

}

TY - GEN

T1 - Toward time resolved 4D cardiac CT imaging with patient dose reduction; estimating the global heart motion

AU - Taguchi, Katsuyuki

AU - Segars, W. Paul

AU - Fung, George S K

AU - Tsui, Benjamin

PY - 2006

Y1 - 2006

N2 - Coronary artery imaging with multi-slice helical computed tomography is a promising noninvasive imaging technique. The current major issues include the insufficient temporal resolution and large patient dose. We propose an image reconstruction method which provides a solution to both of the problems. The method uses an iterative approach repeating the following four steps until the difference between the two projection data sets falls below a certain criteria in step-4: 1) estimating or updating the cardiac motion vectors, 2) reconstructing the time-resolved 4D dynamic volume images using the motion vectors, 3) calculating the projection data from the current 4D images, 4) comparing them with the measured ones. In this study, we obtain the first estimate of the motion vector. We use the 4D NCAT phantom, a realistic computer model for the human anatomy and cardiac motions, to generate the dynamic fan-beam projection data sets as well to provide a known truth for the motion. Then, the halfscan reconstruction with the sliding time-window technique is used to generate cine images: f(t, r). Here, we use one heart beat for each position r so that the time information is retained. Next, the magnitude of the first derivative of f(t, r) with respect to time, i.e., |df/dt|, is calculated and summed over a region-of-interest (ROI), which is called the mean-absolute difference (MAD). The initial estimation of the vector field are obtained using MAD for each ROI. Results of the preliminary study are presented.

AB - Coronary artery imaging with multi-slice helical computed tomography is a promising noninvasive imaging technique. The current major issues include the insufficient temporal resolution and large patient dose. We propose an image reconstruction method which provides a solution to both of the problems. The method uses an iterative approach repeating the following four steps until the difference between the two projection data sets falls below a certain criteria in step-4: 1) estimating or updating the cardiac motion vectors, 2) reconstructing the time-resolved 4D dynamic volume images using the motion vectors, 3) calculating the projection data from the current 4D images, 4) comparing them with the measured ones. In this study, we obtain the first estimate of the motion vector. We use the 4D NCAT phantom, a realistic computer model for the human anatomy and cardiac motions, to generate the dynamic fan-beam projection data sets as well to provide a known truth for the motion. Then, the halfscan reconstruction with the sliding time-window technique is used to generate cine images: f(t, r). Here, we use one heart beat for each position r so that the time information is retained. Next, the magnitude of the first derivative of f(t, r) with respect to time, i.e., |df/dt|, is calculated and summed over a region-of-interest (ROI), which is called the mean-absolute difference (MAD). The initial estimation of the vector field are obtained using MAD for each ROI. Results of the preliminary study are presented.

KW - Cardiac CT

KW - Computed tomography (CT)

KW - Radiation dose

KW - Temporal resolution

UR - http://www.scopus.com/inward/record.url?scp=33745407004&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745407004&partnerID=8YFLogxK

U2 - 10.1117/12.653279

DO - 10.1117/12.653279

M3 - Conference contribution

AN - SCOPUS:33745407004

SN - 0819461857

SN - 9780819461858

VL - 6142 I

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -