Toward a new toxicology - evolution or revolution?

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


This essay summarises the author's thoughts on the current paradigm change in toxicology. The driving factors and mechanisms of this change, and obstacles to it, are discussed. Current developments are discussed on the basis of some key assumptions in Thomas Kuhn's famous book. The Structure of Scientific Revolutions. The author's personal view is that there is clear evidence that revolutionary changes in regulatory toxicology are emerging.

Original languageEnglish (US)
Pages (from-to)635-639
Number of pages5
JournalATLA Alternatives to Laboratory Animals
Issue number6
StatePublished - Dec 2008
Externally publishedYes


  • Alternatives
  • Animal testing
  • New approaches and technologies
  • Philosophy
  • Risk assessment
  • Safety assessment
  • Toxicology

ASJC Scopus subject areas

  • Medicine(all)


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