Total knee arthroplasty in patients with HIV infection

Christopher B. Lynch, Robert S. Sterling

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Purpose of review: With modern medical therapy, the number of patients with HIV infection who require total knee arthroplasty is expected to continue to increase. Previous reports have suggested that the incidence of complications in this population has increased. This review will evaluate the recent literature relating to total knee arthroplasty in patients with HIV infection. Recent findings: HIV-positive patients who receive orthopedic implants after closed fractures or for elective procedures through a healthy soft tissue envelope do not have an increased infection risk, nor does the CD4 count predict infection in this setting. Total knee arthroplasty consistently relieves pain in patients with HIV infection with or without hemophilia. The results of total knee arthroplasty in hemophilic patients are less favorable than in the general population, but there is no proven association between HIV infection and these poorer results. Although CD4 counts have been routinely used to assess infection risk in HIV-positive patients, the association between CD4 count and infection after total knee arthroplasty has not been definitively established. Summary: The recent literature has not confirmed the findings of earlier studies demonstrating that infection with HIV is an independent risk factor for the development of complications after total knee arthroplasty.

Original languageEnglish (US)
Pages (from-to)27-30
Number of pages4
JournalCurrent Opinion in Orthopaedics
Issue number1
StatePublished - Feb 2004
Externally publishedYes


  • Arthroplasty
  • Complications
  • Human immunodeficiency virus

ASJC Scopus subject areas

  • Surgery


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