TY - GEN
T1 - Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study
AU - Abbasi, Nida Itrat
AU - Harvy, Jonathan
AU - Bezerianos, Anastasios
AU - Thakor, Nitish V.
AU - Dragomir, Andrei
N1 - Funding Information:
This work was supported by BMRC SPF grant number APG2013/085 from A*STAR, Singapore and Procter and Gamble, Singapore. + Co First Authors, *Corresponding Author All authors are affiliated with the Singapore Institute for Neurotechnology (SINAPSE), National University of Singapore (NUS). Corresponding author email address: andrei.drag@gmail.com.
Publisher Copyright:
© 2019 IEEE.
PY - 2019/5/16
Y1 - 2019/5/16
N2 - Perception of olfactory stimuli involves complex brain processing which can be directly associated with cognition and emotion. Neural structures embedded deep within the brain and several cortical entities collaborate for the processing of this unique sensory modality. In this study, we investigate the dynamic changes in the neural responses associated with prolonged and repeated exposure to pleasant odor stimuli. Graph metrics computed from EEG functional connectivity like clustering coefficient (p = 0.0008), characteristic path length (p = 0.014) and local efficiency (p = 0.0005) were seen to undergo statistically significant changes, indicating inhibition in the global and local information processing that can be attributed to olfactory adaptation. Moreover, dominant but diminishing activity was observed in the left cerebral hemisphere, signifying recruitment of various neuronal ensembles associated with complex cognitive processes for perception of pleasant odor stimuli.
AB - Perception of olfactory stimuli involves complex brain processing which can be directly associated with cognition and emotion. Neural structures embedded deep within the brain and several cortical entities collaborate for the processing of this unique sensory modality. In this study, we investigate the dynamic changes in the neural responses associated with prolonged and repeated exposure to pleasant odor stimuli. Graph metrics computed from EEG functional connectivity like clustering coefficient (p = 0.0008), characteristic path length (p = 0.014) and local efficiency (p = 0.0005) were seen to undergo statistically significant changes, indicating inhibition in the global and local information processing that can be attributed to olfactory adaptation. Moreover, dominant but diminishing activity was observed in the left cerebral hemisphere, signifying recruitment of various neuronal ensembles associated with complex cognitive processes for perception of pleasant odor stimuli.
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U2 - 10.1109/NER.2019.8717167
DO - 10.1109/NER.2019.8717167
M3 - Conference contribution
AN - SCOPUS:85066745069
T3 - International IEEE/EMBS Conference on Neural Engineering, NER
SP - 635
EP - 638
BT - 9th International IEEE EMBS Conference on Neural Engineering, NER 2019
PB - IEEE Computer Society
T2 - 9th International IEEE EMBS Conference on Neural Engineering, NER 2019
Y2 - 20 March 2019 through 23 March 2019
ER -