Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study

Nida Itrat Abbasi; Jonathan Harvy; Anastasios Bezerianos; Nitish V. Thakor; Andrei Dragomir

doi:10.1109/NER.2019.8717167

Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study

Nida Itrat Abbasi, Jonathan Harvy, Anastasios Bezerianos, Nitish V. Thakor, Andrei Dragomir

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Perception of olfactory stimuli involves complex brain processing which can be directly associated with cognition and emotion. Neural structures embedded deep within the brain and several cortical entities collaborate for the processing of this unique sensory modality. In this study, we investigate the dynamic changes in the neural responses associated with prolonged and repeated exposure to pleasant odor stimuli. Graph metrics computed from EEG functional connectivity like clustering coefficient (p = 0.0008), characteristic path length (p = 0.014) and local efficiency (p = 0.0005) were seen to undergo statistically significant changes, indicating inhibition in the global and local information processing that can be attributed to olfactory adaptation. Moreover, dominant but diminishing activity was observed in the left cerebral hemisphere, signifying recruitment of various neuronal ensembles associated with complex cognitive processes for perception of pleasant odor stimuli.

Original language	English (US)
Title of host publication	9th International IEEE EMBS Conference on Neural Engineering, NER 2019
Publisher	IEEE Computer Society
Pages	635-638
Number of pages	4
ISBN (Electronic)	9781538679210
DOIs	https://doi.org/10.1109/NER.2019.8717167
State	Published - May 16 2019
Event	9th International IEEE EMBS Conference on Neural Engineering, NER 2019 - San Francisco, United States Duration: Mar 20 2019 → Mar 23 2019

Publication series

Name	International IEEE/EMBS Conference on Neural Engineering, NER
Volume	2019-March
ISSN (Print)	1948-3546
ISSN (Electronic)	1948-3554

Conference

Conference	9th International IEEE EMBS Conference on Neural Engineering, NER 2019
Country	United States
City	San Francisco
Period	3/20/19 → 3/23/19

ASJC Scopus subject areas

Artificial Intelligence
Mechanical Engineering

Access to Document

10.1109/NER.2019.8717167

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Abbasi, N. I., Harvy, J., Bezerianos, A., Thakor, N. V., & Dragomir, A. (2019). Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study. In 9th International IEEE EMBS Conference on Neural Engineering, NER 2019 (pp. 635-638). [8717167] (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2019-March). IEEE Computer Society. https://doi.org/10.1109/NER.2019.8717167

Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study. / Abbasi, Nida Itrat; Harvy, Jonathan; Bezerianos, Anastasios; Thakor, Nitish V.; Dragomir, Andrei.

9th International IEEE EMBS Conference on Neural Engineering, NER 2019. IEEE Computer Society, 2019. p. 635-638 8717167 (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2019-March).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abbasi, NI, Harvy, J, Bezerianos, A, Thakor, NV & Dragomir, A 2019, Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study. in 9th International IEEE EMBS Conference on Neural Engineering, NER 2019., 8717167, International IEEE/EMBS Conference on Neural Engineering, NER, vol. 2019-March, IEEE Computer Society, pp. 635-638, 9th International IEEE EMBS Conference on Neural Engineering, NER 2019, San Francisco, United States, 3/20/19. https://doi.org/10.1109/NER.2019.8717167

Abbasi NI, Harvy J, Bezerianos A, Thakor NV, Dragomir A. Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study. In 9th International IEEE EMBS Conference on Neural Engineering, NER 2019. IEEE Computer Society. 2019. p. 635-638. 8717167. (International IEEE/EMBS Conference on Neural Engineering, NER). https://doi.org/10.1109/NER.2019.8717167

Abbasi, Nida Itrat ; Harvy, Jonathan ; Bezerianos, Anastasios ; Thakor, Nitish V. ; Dragomir, Andrei. / Topological Re-Organisation of the Brain Connectivity during Olfactory Adaptation - An EEG Functional Connectome Study. 9th International IEEE EMBS Conference on Neural Engineering, NER 2019. IEEE Computer Society, 2019. pp. 635-638 (International IEEE/EMBS Conference on Neural Engineering, NER).

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abstract = "Perception of olfactory stimuli involves complex brain processing which can be directly associated with cognition and emotion. Neural structures embedded deep within the brain and several cortical entities collaborate for the processing of this unique sensory modality. In this study, we investigate the dynamic changes in the neural responses associated with prolonged and repeated exposure to pleasant odor stimuli. Graph metrics computed from EEG functional connectivity like clustering coefficient (p = 0.0008), characteristic path length (p = 0.014) and local efficiency (p = 0.0005) were seen to undergo statistically significant changes, indicating inhibition in the global and local information processing that can be attributed to olfactory adaptation. Moreover, dominant but diminishing activity was observed in the left cerebral hemisphere, signifying recruitment of various neuronal ensembles associated with complex cognitive processes for perception of pleasant odor stimuli.",

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