Topological changes of the effective connectivity during the working memory training

Yu Sun, Fumihiko Taya, Yu Chen, Ignacio Delgado Martinez, Nitish Thakor, Anastasios Bezerianos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Working memory (WM) refers to the retention of information over a short period of time. Accumulated evidence showed that training WM would lead to beneficial effects in untrained tasks, which could be attributed to the strengthening of the functional connections between brain regions through repeated training task. In this proof of concept investigation, we applied a graph theoretical approach to analyze the early changes of functional connectivity from two subjects undergoing a spatial n-back WM training task for three continuous days. A significant decreased clustering coefficient and normalized shortest path length was revealed, suggesting a reduced local efficiency with an increased global efficiency after WM training. Our findings thereby provide insightful implications for understanding the mechanisms of brain dynamics in cognitive training.

Original languageEnglish (US)
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages6242-6245
Number of pages4
ISBN (Electronic)9781424479290
DOIs
StatePublished - Nov 2 2014
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: Aug 26 2014Aug 30 2014

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period8/26/148/30/14

    Fingerprint

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

Cite this

Sun, Y., Taya, F., Chen, Y., Delgado Martinez, I., Thakor, N., & Bezerianos, A. (2014). Topological changes of the effective connectivity during the working memory training. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 6242-6245). [6945055] (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6945055