TY - GEN
T1 - Topological changes of the effective connectivity during the working memory training
AU - Sun, Yu
AU - Taya, Fumihiko
AU - Chen, Yu
AU - Delgado Martinez, Ignacio
AU - Thakor, Nitish
AU - Bezerianos, Anastasios
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2014/11/2
Y1 - 2014/11/2
N2 - Working memory (WM) refers to the retention of information over a short period of time. Accumulated evidence showed that training WM would lead to beneficial effects in untrained tasks, which could be attributed to the strengthening of the functional connections between brain regions through repeated training task. In this proof of concept investigation, we applied a graph theoretical approach to analyze the early changes of functional connectivity from two subjects undergoing a spatial n-back WM training task for three continuous days. A significant decreased clustering coefficient and normalized shortest path length was revealed, suggesting a reduced local efficiency with an increased global efficiency after WM training. Our findings thereby provide insightful implications for understanding the mechanisms of brain dynamics in cognitive training.
AB - Working memory (WM) refers to the retention of information over a short period of time. Accumulated evidence showed that training WM would lead to beneficial effects in untrained tasks, which could be attributed to the strengthening of the functional connections between brain regions through repeated training task. In this proof of concept investigation, we applied a graph theoretical approach to analyze the early changes of functional connectivity from two subjects undergoing a spatial n-back WM training task for three continuous days. A significant decreased clustering coefficient and normalized shortest path length was revealed, suggesting a reduced local efficiency with an increased global efficiency after WM training. Our findings thereby provide insightful implications for understanding the mechanisms of brain dynamics in cognitive training.
UR - http://www.scopus.com/inward/record.url?scp=84929492375&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929492375&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2014.6945055
DO - 10.1109/EMBC.2014.6945055
M3 - Conference contribution
C2 - 25571423
AN - SCOPUS:84929492375
T3 - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
SP - 6242
EP - 6245
BT - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Y2 - 26 August 2014 through 30 August 2014
ER -