Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima; Shannon Chan; Jonathan Powell; Joseph A. Napoli; Andrew W. Walter; Thomas J. Walsh

doi:10.1097/MPH.0000000000000166

Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima, Shannon Chan, Jonathan Powell, Joseph A. Napoli, Andrew W. Walter, Thomas J. Walsh

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

During chemotherapy for bilineal leukemia, a 6-monthold infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

Original language	English (US)
Pages (from-to)	e468-e470
Journal	Journal of Pediatric Hematology/Oncology
Volume	36
Issue number	7
DOIs	https://doi.org/10.1097/MPH.0000000000000166
State	Published - Oct 8 2014

Keywords

Bilineal leukemia
Mucormycosis
Rhizopus
Topical amphotericin B

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1097/MPH.0000000000000166

Cite this

Di Pentima, M. C., Chan, S., Powell, J., Napoli, J. A., Walter, A. W., & Walsh, T. J. (2014). Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review. Journal of Pediatric Hematology/Oncology, 36(7), e468-e470. https://doi.org/10.1097/MPH.0000000000000166

Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia : Case report and review. / Di Pentima, Maria C.; Chan, Shannon; Powell, Jonathan; Napoli, Joseph A.; Walter, Andrew W.; Walsh, Thomas J.

In: Journal of Pediatric Hematology/Oncology, Vol. 36, No. 7, 08.10.2014, p. e468-e470.

Research output: Contribution to journal › Article › peer-review

Di Pentima, MC, Chan, S, Powell, J, Napoli, JA, Walter, AW & Walsh, TJ 2014, 'Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review', Journal of Pediatric Hematology/Oncology, vol. 36, no. 7, pp. e468-e470. https://doi.org/10.1097/MPH.0000000000000166

Di Pentima, Maria C. ; Chan, Shannon ; Powell, Jonathan ; Napoli, Joseph A. ; Walter, Andrew W. ; Walsh, Thomas J. / Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia : Case report and review. In: Journal of Pediatric Hematology/Oncology. 2014 ; Vol. 36, No. 7. pp. e468-e470.

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abstract = "During chemotherapy for bilineal leukemia, a 6-monthold infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.",

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Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Abstract

Keywords

ASJC Scopus subject areas

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