Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima, Shannon Chan, Jonathan Powell, Joseph A. Napoli, Andrew W. Walter, Thomas J. Walsh

Research output: Contribution to journalArticle

Abstract

During chemotherapy for bilineal leukemia, a 6-monthold infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

Original languageEnglish (US)
Pages (from-to)e468-e470
JournalJournal of Pediatric Hematology/Oncology
Volume36
Issue number7
StatePublished - Oct 8 2014
Externally publishedYes

Fingerprint

Mucormycosis
Topical Administration
Rhizopus
Soft Tissue Infections
Thoracic Wall
Amphotericin B
Leukemia
Drug Therapy
Skin
Wounds and Injuries
Therapeutics
liposomal amphotericin B
deoxycholate drug combination amphotericin B

Keywords

  • Bilineal leukemia
  • Mucormycosis
  • Rhizopus
  • Topical amphotericin B

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia : Case report and review. / Di Pentima, Maria C.; Chan, Shannon; Powell, Jonathan; Napoli, Joseph A.; Walter, Andrew W.; Walsh, Thomas J.

In: Journal of Pediatric Hematology/Oncology, Vol. 36, No. 7, 08.10.2014, p. e468-e470.

Research output: Contribution to journalArticle

Di Pentima, Maria C. ; Chan, Shannon ; Powell, Jonathan ; Napoli, Joseph A. ; Walter, Andrew W. ; Walsh, Thomas J. / Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia : Case report and review. In: Journal of Pediatric Hematology/Oncology. 2014 ; Vol. 36, No. 7. pp. e468-e470.
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