Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima, Shannon Chan, Jonathan Powell, Joseph A. Napoli, Andrew W. Walter, Thomas J. Walsh

Research output: Contribution to journalArticle

Abstract

During chemotherapy for bilineal leukemia, a 6-monthold infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

Original languageEnglish (US)
Pages (from-to)e468-e470
JournalJournal of Pediatric Hematology/Oncology
Volume36
Issue number7
DOIs
StatePublished - Oct 8 2014

Keywords

  • Bilineal leukemia
  • Mucormycosis
  • Rhizopus
  • Topical amphotericin B

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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