Líquido amniótico tópico: Uma potencial nova alternativa para doenças da superfície ocular

Translated title of the contribution: Topical amniotic fluid: A potential new alternative for ocular surface diseases

Guilherme Goulart Quinto, Suy Anne Rebouças Martins, Renata Tiemi, Mauro Campos, Ashley Behrens

Research output: Contribution to journalArticle

Abstract

Amniotic fluid bathes the fetus during intrauterine life and is in permanent contact with the fetal ocular surface in this important period of development. It contains a series of growth factors that may have multiple effects on the wound healing process. These factors are thought to accelerate the recovery of corneal sensitivity and nerve regeneration after keratorefractive procedures, and also may control scar formation and balance the ocular surface after topical application. Hundreds of different proteins have been identified in the human amniotic fluid, and the role of each still not quite understood. The outcomes obtained so far with amniotic fluid application to ocular surface diseases suggest a promising therapy. Research is underway to identify the effects of specific factors of the amniotic fluid in ocular inflammation. The purpose of this review is to report the properties and current utilizations of amniotic fluid as well as to summarize the recent studies related to the use of this fluid for ocular surface diseases.

Translated title of the contributionTopical amniotic fluid: A potential new alternative for ocular surface diseases
Original languagePortuguese
Pages (from-to)55-60
Number of pages6
JournalArquivos brasileiros de oftalmologia
Volume71
Issue number6 SUPP
DOIs
StatePublished - 2009

Keywords

  • Amniotic fluid
  • Corneal diseases/therapy
  • Ophthalmic solutions/therapeutic use
  • Wound healing

ASJC Scopus subject areas

  • Ophthalmology

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