TY - JOUR
T1 - Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants
T2 - A genomic perspective
AU - Jebanathirajah, Judith A.
AU - Peri, Suraj
AU - Pandey, Akhilesh
PY - 2002/9/1
Y1 - 2002/9/1
N2 - Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.
AB - Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.
UR - http://www.scopus.com/inward/record.url?scp=0036730113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036730113&partnerID=8YFLogxK
U2 - 10.1016/S1360-1385(02)02309-9
DO - 10.1016/S1360-1385(02)02309-9
M3 - Article
C2 - 12234729
AN - SCOPUS:0036730113
SN - 1360-1385
VL - 7
SP - 388
EP - 391
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 9
ER -