Tobacco craving in smokers with and without schizophrenia

Suzanne Lo, Stephen J. Heishman, Heather Raley, Katherine Wright, Heidi J. Wehring, Eric T. Moolchan, Stephanie Feldman, Fang Liu, Robert P. McMahon, Charles M. Richardson, Deanna L. Kelly

Research output: Contribution to journalArticle

Abstract

We examined tobacco craving and dependence in current smokers (18-65 years) with schizophrenia (N= 100) and those without a psychiatric disorder (normal controls, N= 100). During the 2-3 h visit participants completed demographic and smoking-related questionnaires and provided a breath CO sample. The Tobacco Craving Questionnaire-Short Form (TCQ-SF) was administered. Immediately after smoking one cigarette, no difference in TCQ-SF total score was noted (46.7 ± 19.5 schizophrenia, 42.8 ± 18.2 controls, p= 0.15); however, after 15 min TCQ-SF total score was significantly higher in people with schizophrenia (50.0 ± 19.6) than in controls (38.6 ± 19.4) (p= 0.0014). TCQ-SF factors of emotionality (p= 0.0015), compulsivity (p= 0.0003) and purposefulness (p= 0.0174) were significantly greater in the schizophrenia group than the control group. FTND scores (5.5 ± 2.0 vs 5.3 ± 2.0, p= 0.62) number of cigarettes smoked daily (17.9 ± 11.6 vs. 17.0 ± 7.9), expired breath CO (28.0 ± 14.5. ppm vs. 22.0 ± 8.0. ppm) and age at smoking initiation (16.2 ± 5.4 vs. 15.6 ± 5.5. years, p= 0.44) did not differ in the schizophrenia and control groups respectively. In conclusion, tobacco craving as measured by the TCQ-SF was significantly greater in people with schizophrenia than controls 15 min post-smoking, despite similar scores in dependence and similar smoking histories and current smoking patterns.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalSchizophrenia Research
Volume127
Issue number1-3
DOIs
StatePublished - Apr 2011
Externally publishedYes

Fingerprint

Tobacco
Schizophrenia
Smoking
Carbon Monoxide
Tobacco Use Disorder
Control Groups
Craving
Tobacco Products
Psychiatry
Surveys and Questionnaires
Demography

Keywords

  • Craving
  • Dependency
  • Nicotine
  • Schizophrenia
  • Smoking

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Lo, S., Heishman, S. J., Raley, H., Wright, K., Wehring, H. J., Moolchan, E. T., ... Kelly, D. L. (2011). Tobacco craving in smokers with and without schizophrenia. Schizophrenia Research, 127(1-3), 241-245. https://doi.org/10.1016/j.schres.2010.06.017

Tobacco craving in smokers with and without schizophrenia. / Lo, Suzanne; Heishman, Stephen J.; Raley, Heather; Wright, Katherine; Wehring, Heidi J.; Moolchan, Eric T.; Feldman, Stephanie; Liu, Fang; McMahon, Robert P.; Richardson, Charles M.; Kelly, Deanna L.

In: Schizophrenia Research, Vol. 127, No. 1-3, 04.2011, p. 241-245.

Research output: Contribution to journalArticle

Lo, S, Heishman, SJ, Raley, H, Wright, K, Wehring, HJ, Moolchan, ET, Feldman, S, Liu, F, McMahon, RP, Richardson, CM & Kelly, DL 2011, 'Tobacco craving in smokers with and without schizophrenia', Schizophrenia Research, vol. 127, no. 1-3, pp. 241-245. https://doi.org/10.1016/j.schres.2010.06.017
Lo S, Heishman SJ, Raley H, Wright K, Wehring HJ, Moolchan ET et al. Tobacco craving in smokers with and without schizophrenia. Schizophrenia Research. 2011 Apr;127(1-3):241-245. https://doi.org/10.1016/j.schres.2010.06.017
Lo, Suzanne ; Heishman, Stephen J. ; Raley, Heather ; Wright, Katherine ; Wehring, Heidi J. ; Moolchan, Eric T. ; Feldman, Stephanie ; Liu, Fang ; McMahon, Robert P. ; Richardson, Charles M. ; Kelly, Deanna L. / Tobacco craving in smokers with and without schizophrenia. In: Schizophrenia Research. 2011 ; Vol. 127, No. 1-3. pp. 241-245.
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abstract = "We examined tobacco craving and dependence in current smokers (18-65 years) with schizophrenia (N= 100) and those without a psychiatric disorder (normal controls, N= 100). During the 2-3 h visit participants completed demographic and smoking-related questionnaires and provided a breath CO sample. The Tobacco Craving Questionnaire-Short Form (TCQ-SF) was administered. Immediately after smoking one cigarette, no difference in TCQ-SF total score was noted (46.7 ± 19.5 schizophrenia, 42.8 ± 18.2 controls, p= 0.15); however, after 15 min TCQ-SF total score was significantly higher in people with schizophrenia (50.0 ± 19.6) than in controls (38.6 ± 19.4) (p= 0.0014). TCQ-SF factors of emotionality (p= 0.0015), compulsivity (p= 0.0003) and purposefulness (p= 0.0174) were significantly greater in the schizophrenia group than the control group. FTND scores (5.5 ± 2.0 vs 5.3 ± 2.0, p= 0.62) number of cigarettes smoked daily (17.9 ± 11.6 vs. 17.0 ± 7.9), expired breath CO (28.0 ± 14.5. ppm vs. 22.0 ± 8.0. ppm) and age at smoking initiation (16.2 ± 5.4 vs. 15.6 ± 5.5. years, p= 0.44) did not differ in the schizophrenia and control groups respectively. In conclusion, tobacco craving as measured by the TCQ-SF was significantly greater in people with schizophrenia than controls 15 min post-smoking, despite similar scores in dependence and similar smoking histories and current smoking patterns.",
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