TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers

M. Ptito, A. Fumal, A. Martens De Noordhout, J. Schoenen, A. Gjedde, R. Kupers

Research output: Contribution to journalArticle

Abstract

Various non-visual inputs produce cross-modal responses in the visual cortex of early blind subjects. In order to determine the qualitative experience associated with these occipital activations, we systematically stimulated the entire occipital cortex using single pulse transcranial magnetic stimulation (TMS) in early blind subjects and in blindfolded seeing controls. Whereas blindfolded seeing controls reported only phosphenes following occipital cortex stimulation, some of the blind subjects reported tactile sensations in the fingers that were somatotopically organized onto the visual cortex. The number of cortical sites inducing tactile sensations appeared to be related to the number of hours of Braille reading per day, Braille reading speed and dexterity. These data, taken in conjunction with previous anatomical, behavioural and functional imaging results, suggest the presence of a polysynaptic cortical pathway between the somatosensory cortex and the visual cortex in early blind subjects. These results also add new evidence that the activity of the occipital lobe in the blind takes its qualitative expression from the character of its new input source, therefore supporting the cortical deference hypothesis.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalExperimental Brain Research
Volume184
Issue number2
DOIs
StatePublished - Jan 2008
Externally publishedYes

Fingerprint

Occipital Lobe
Transcranial Magnetic Stimulation
Touch
Visual Cortex
Fingers
Reading
Phosphenes
Somatosensory Cortex

Keywords

  • Cortical deference
  • Cross-modal plasticity
  • Early blindness
  • Qualia
  • Visual cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Ptito, M., Fumal, A., De Noordhout, A. M., Schoenen, J., Gjedde, A., & Kupers, R. (2008). TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers. Experimental Brain Research, 184(2), 193-200. https://doi.org/10.1007/s00221-007-1091-0

TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers. / Ptito, M.; Fumal, A.; De Noordhout, A. Martens; Schoenen, J.; Gjedde, A.; Kupers, R.

In: Experimental Brain Research, Vol. 184, No. 2, 01.2008, p. 193-200.

Research output: Contribution to journalArticle

Ptito, M, Fumal, A, De Noordhout, AM, Schoenen, J, Gjedde, A & Kupers, R 2008, 'TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers', Experimental Brain Research, vol. 184, no. 2, pp. 193-200. https://doi.org/10.1007/s00221-007-1091-0
Ptito, M. ; Fumal, A. ; De Noordhout, A. Martens ; Schoenen, J. ; Gjedde, A. ; Kupers, R. / TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers. In: Experimental Brain Research. 2008 ; Vol. 184, No. 2. pp. 193-200.
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