Timing of oocyte retrieval in cycles with a spontaneous luteinizing hormone surge in a large in vitro fertilization program

K. Droesch, S. J. Muasher, D. Kreiner, G. Seegar Jones, A. A. Acosta, Z. Rosenwaks

Research output: Contribution to journalArticlepeer-review

Abstract

Forty-four cycles with a spontaneous luteinizing hormone (LH) surge among 377 in vitro fertilization (IVF) patients were studied for outcome with different timing of oocyte retrieval. Mean number of preovulatory oocytes per retrieval and per transfer was significantly less in these cycles than in controls. Mean number of preovulatory oocytes per retrieval and per transfer was significantly higher when the human chorionic gonadotropin (hCG)-retrieval interval was >35 hours, compared with <24 hours. In cycles with an hCG-retrieval interval of <24 hours, percentage of preovulatory oocytes was higher when serum estradiol (E2) decreased by >15% on the morning after hCG administration compared with a plateau or an increase in serum E2. Timing oocyte retrieval after spontaneous LH surge should consider the hCG-retrieval interval and changes in E2 levels after hCG administration; this may avoid cancellation for many patients.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalFertility and sterility
Volume50
Issue number3
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Timing of oocyte retrieval in cycles with a spontaneous luteinizing hormone surge in a large in vitro fertilization program'. Together they form a unique fingerprint.

Cite this