Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Sven D. Sommerfeld, Jennifer H. Elisseeff

Research output: Contribution to journalShort survey


Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.

Original languageEnglish (US)
Pages (from-to)166-167
Number of pages2
JournalCell stem cell
Issue number2
StatePublished - Feb 4 2016


ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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