Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Sven D. Sommerfeld, Jennifer H. Elisseeff

Research output: Contribution to journalShort surveypeer-review

Abstract

Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.

Original languageEnglish (US)
Pages (from-to)166-167
Number of pages2
JournalCell stem cell
Volume18
Issue number2
DOIs
StatePublished - Feb 4 2016

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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