Time-of-flight precision and PET image accuracy

Jeffrey A. Kolthammer, Jing Tang, Amy E. Perkins, Raymond F. Muzic

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Time of flight information is used in PET to improve image quality. However, the nature of the improvement and its relationship with the precision of the time of flight measurement remains to be well-characterized, particularly in the framework of iterative reconstruction. In this work, hot-spheres phantoms are imaged, and the list data are then degraded to simulate systems with poorer timing resolution. More precise of flight is found to lead to images with higher sphere contrast and lower background noise at each iteration, and convergent sphere contrast with fewer iterations. Combining these effects, the background noise at which each sphere reaches 90% of its final contrast is lower with improved timing resolution, with the amount of noise reduction underestimated by a conventional proportionality to the timing resolution.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010
Pages3657-3660
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 - Knoxville, TN, United States
Duration: Oct 30 2010Nov 6 2010

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010
CountryUnited States
CityKnoxville, TN
Period10/30/1011/6/10

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Kolthammer, J. A., Tang, J., Perkins, A. E., & Muzic, R. F. (2010). Time-of-flight precision and PET image accuracy. In IEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010 (pp. 3657-3660). [5874495] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2010.5874495