Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle

Howard A Zacur, R. Genadry, J. A. Rock, T. M. King, B. R. Smith, G. V. Foster

Research output: Contribution to journalArticle

Abstract

Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume61
Issue number4
StatePublished - 1985

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Thyrotropin-Releasing Hormone
Muscle
Pressure
Muscles
Muscle Contraction
Urogenital System
Urinary Bladder
Injections

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Zacur, H. A., Genadry, R., Rock, J. A., King, T. M., Smith, B. R., & Foster, G. V. (1985). Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle. Journal of Clinical Endocrinology and Metabolism, 61(4), 787-789.

Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle. / Zacur, Howard A; Genadry, R.; Rock, J. A.; King, T. M.; Smith, B. R.; Foster, G. V.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 61, No. 4, 1985, p. 787-789.

Research output: Contribution to journalArticle

Zacur, HA, Genadry, R, Rock, JA, King, TM, Smith, BR & Foster, GV 1985, 'Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle', Journal of Clinical Endocrinology and Metabolism, vol. 61, no. 4, pp. 787-789.
Zacur, Howard A ; Genadry, R. ; Rock, J. A. ; King, T. M. ; Smith, B. R. ; Foster, G. V. / Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle. In: Journal of Clinical Endocrinology and Metabolism. 1985 ; Vol. 61, No. 4. pp. 787-789.
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