Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle

Howard A. Zacur, Rene Genadry, John A. Rock, Theodore M. King, Beverly R. Smith, Giraud V. Foster

Research output: Contribution to journalArticle

Abstract

Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.(J Clin Endocrinol Metab 61 : 787, 1985).

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume61
Issue number4
DOIs
StatePublished - Oct 1985

    Fingerprint

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this