Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle

Howard A. Zacur; Rene Genadry; John A. Rock; Theodore M. King; Beverly R. Smith; Giraud V. Foster

doi:10.1210/jcem-61-4-787

Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle

Howard A. Zacur, Rene Genadry, John A. Rock, Theodore M. King, Beverly R. Smith, Giraud V. Foster

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.(J Clin Endocrinol Metab 61 : 787, 1985).

Original language	English (US)
Pages (from-to)	787-789
Number of pages	3
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	61
Issue number	4
DOIs	https://doi.org/10.1210/jcem-61-4-787
State	Published - Oct 1985

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

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10.1210/jcem-61-4-787

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title = "Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle",

abstract = "Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.(J Clin Endocrinol Metab 61 : 787, 1985).",

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AU - Rock, John A.

AU - King, Theodore M.

AU - Smith, Beverly R.

AU - Foster, Giraud V.

PY - 1985/10

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N2 - Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.(J Clin Endocrinol Metab 61 : 787, 1985).

AB - Pressure studies were carried out in 10 women to determine whether TRH stimulates muscular contractions in the genitourinary system. TRH (500 μg) or saline was administered iv as a bolus injection. Whereas saline had no effect, TRH increased intraurethral pressures in all women, vaginal pressure in 7, and bladder pressure in none. These findings suggest that TRH, acting centrally, peripherally, or both, may play a role in initiating muscular contractions in the female genitourinary tract.(J Clin Endocrinol Metab 61 : 787, 1985).

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Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle

Abstract

ASJC Scopus subject areas

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